Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Oxycodone
Drug ID BADD_D01645
Description Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.[A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.[L6460]
Indications and Usage For the treatment of diarrhoea, pulmonary oedema and for the relief of moderate to moderately severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AA05
DrugBank ID DB00497
KEGG ID D05312
MeSH ID D010098
PubChem ID 5284603
TTD Drug ID D07WPQ
NDC Product Code 68071-5055; 0904-7180; 65162-047; 24510-115; 24510-130; 67651-0304; 65162-050; 71335-1023; 67651-0306; 67651-0305; 71335-0981; 24510-140; 71335-1080; 65162-051; 24510-120; 65162-048; 67877-625; 71335-0677; 65162-049; 67651-0303; 24510-110; 67877-623; 0904-6966; 67651-0302
Synonyms Oxycodone | Dihydrone | Oxycone | Dihydrohydroxycodeinone | Oxycodeinon | Eucodal | Theocodin | Oxycodone Hydrochloride | Oxycontin | Pancodine | Dinarkon | Oxiconum
Chemical Information
Molecular Formula C18H21NO4
CAS Registry Number 76-42-6
SMILES CN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)OC)O4)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Fatigue08.01.01.002--
Fear19.06.03.001--Not Available
Febrile neutropenia01.02.03.002; 08.05.02.004--
Feeling abnormal08.01.09.0140.001857%Not Available
Feeling cold08.01.09.0080.000186%Not Available
Feeling hot08.01.09.0090.000232%Not Available
Feeling jittery08.01.09.0160.000325%Not Available
Femur fracture12.04.01.003; 15.08.03.003--Not Available
Flatulence07.01.04.0020.000232%
Fluid retention14.05.06.002; 20.01.02.003--Not Available
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Folate deficiency14.12.02.0060.000093%Not Available
Foot fracture15.08.03.012; 12.04.01.0120.000371%Not Available
Formication19.10.02.010; 17.02.06.0180.000232%Not Available
Frequent bowel movements07.02.04.0020.000186%Not Available
Gait disturbance17.02.05.016; 08.01.02.0020.001160%
Gallbladder cancer16.07.05.001; 09.04.02.0050.000024%Not Available
Gallbladder disorder09.03.02.0010.000232%Not Available
Gamma-glutamyltransferase increased13.03.01.011--
Gastric atony07.02.02.009--Not Available
Gastric cancer16.13.03.001; 07.21.02.0010.000073%Not Available
Gastritis07.08.02.001--
Gastrooesophageal reflux disease07.02.02.0030.000325%
Gastroenteritis viral11.05.04.005; 07.19.03.0050.000139%Not Available
Gastrointestinal carcinoma16.13.04.001; 07.21.03.0010.000024%Not Available
Gastrointestinal disorder07.11.01.0010.000557%Not Available
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Gastrointestinal pain07.01.05.005--
Generalised oedema14.05.06.007; 08.01.07.004--
Gingival bleeding24.07.02.010; 07.09.07.001--Not Available
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