Drug Name |
Nystatin |
Drug ID |
BADD_D01591 |
Description |
Nystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notably _Candida_ species.[L10686] It is one of the most effective antifungal agents synthesized by bacteria, in this case a strain of _Streptomyces noursei_,[L10776] and is closely related to [amphotericin B], differing only slightly in structure.[A188562] Nystatin has a greater antifungal activity than amphotericin B - parenterally administered nystatin, however, is associated with significant toxicity and is not available in a formulation appropriate for systemic use.[A188562] As it undergoes very little absorption following oral or topical administration, nystatin's efficacy is limited to the treatment/prevention of cutaneous, mucocutaneous, and gastrointestinal fungal infections.[L10686,L10728] |
Indications and Usage |
For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species |
Marketing Status |
Prescription; Discontinued |
ATC Code |
A07AA02; D01AA01; G01AA01 |
DrugBank ID |
DB00646
|
KEGG ID |
D00202
|
MeSH ID |
D009761
|
PubChem ID |
11286230
|
TTD Drug ID |
D08XAC
|
NDC Product Code |
0574-2008; 60432-537; 68071-4293; 55154-1578; 68788-6792; 63629-2492; 13668-534; 51552-0041; 68788-7949; 71205-106; 50090-2763; 75834-235; 62991-2785; 68071-2556; 0168-0054; 70518-3284; 68308-152; 33342-481; 23155-051; 51672-1289; 55154-5788; 76003-0827; 79572-026; 50090-2854; 53734-336; 63187-422; 69315-307; 61813-701; 63629-8520; 66267-953; 51927-0095; 0832-0465; 63187-464; 0121-0868; 63629-2516; 63629-8521; 69315-306; 0121-0810; 61813-702; 63629-8697; 39822-3015; 76003-9999; 63629-2493; 16714-769; 70771-1585; 53002-8220; 50090-1740; 70771-1357; 0168-0007; 13668-595; 72578-089; 66689-008; 72189-046; 68071-2621; 0121-4810; 68094-599; 45802-048; 68788-9516; 63629-2515; 55154-4056; 63629-8698; 70166-331; 72189-278; 61813-801; 65415-1372; 66689-037; 0472-0166; 42291-651; 63187-703; 63629-8696; 63629-8695; 51672-4117; 50090-5221; 45802-059; 71205-575; 61813-802; 68382-370; 50090-5845; 63629-8350; 50090-0233; 50090-3799; 17856-0811; 33342-469; 38779-0242; 53489-400; 50090-5237; 66267-952; 50383-587; 50090-3772; 65415-1371; 63629-8694; 50090-5315; 0093-0983; 42934-400; 43386-530; 63629-8519; 63187-847 |
Synonyms |
Nystatin | Fungicidin | Mycostatin | Stamicin | Nystatin A1 | Nystatin A2 | Nystatin A3 | Nystatin G | Stamycin | Nilstat |