Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Nitrous oxide
Drug ID BADD_D01580
Description Nitrous oxide, commonly known as "laughing gas", is a chemical compound with the chemical formula N2O. At room temperature, it is a colorless non-flammable gas, with a pleasant, slightly sweet odor and taste. It is used in surgery and dentistry for its anesthetic and analgesic effects. It is known as "laughing gas" due to the euphoric effects of inhaling it, a property that has led to its recreational use as an inhalant drug.
Indications and Usage Not Available
Marketing Status approved; vet_approved
ATC Code N01AX13
DrugBank ID DB06690
KEGG ID D00102
MeSH ID D009609
PubChem ID 948
TTD Drug ID D0O8DI
NDC Product Code 12121-002; 21220-122; 42602-003; 51486-007; 55037-301; 55404-002; 72343-001; 10736-017; 33335-003; 44076-012; 46123-007; 12213-593; 18482-002; 20703-003; 34057-010; 10014-003; 46123-006; 53440-003; 63978-201; 24312-003; 48273-002; 49575-003; 54218-800; 62273-005; 67477-002; 17575-011; 43621-003; 55050-0018; 70151-004; 44517-020; 50554-005; 62097-0004; 67525-400; 10167-200; 11054-007; 46362-003; 52086-015; 62045-8333; 72276-002; 10252-003; 52568-002; 53511-003; 54260-001; 59579-004
UNII K50XQU1029
Synonyms Nitrous Oxide | Oxide, Nitrous | Laughing Gas | Gas, Laughing | Nitrogen Protoxide
Chemical Information
Molecular Formula N2O
CAS Registry Number 10024-97-2
SMILES [N-]=[N+]=O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Thrombocytopenia01.08.01.002--Not Available
Tremor17.01.06.0020.000268%
Vertigo17.02.12.002; 04.04.01.0030.000179%
Vitamin B12 deficiency14.12.02.0040.002233%Not Available
Vomiting07.01.07.003--
Quadriparesis17.01.04.0120.000179%Not Available
Balance disorder08.01.03.081; 17.02.02.0070.000179%Not Available
Pneumomediastinum22.09.03.0040.000357%Not Available
Peripheral sensorimotor neuropathy17.09.03.0090.000357%Not Available
Cognitive disorder19.21.02.001; 17.03.03.0030.000357%
Metabolic disorder14.11.01.0010.000179%Not Available
Motor dysfunction15.05.06.006; 17.01.02.0310.000268%Not Available
Central nervous system stimulation25.04.01.001--Not Available
Demyelinating polyneuropathy17.09.04.003; 10.04.10.0070.000357%Not Available
Psychotic disorder19.03.01.0020.000179%
Arterial occlusive disease24.04.02.0210.000179%Not Available
Bone marrow failure01.03.03.005--
Substance abuse19.07.06.0180.000714%Not Available
Vascular resistance pulmonary increased13.14.03.020--Not Available
Occupational exposure to product12.03.06.001--Not Available
Subacute combined cord degeneration14.12.02.011; 01.03.01.007; 17.10.01.0210.004376%Not Available
Hyperhomocysteinaemia14.10.02.003; 01.01.02.0210.000447%Not Available
Choroidal infarction24.04.09.010; 06.10.03.0030.000357%Not Available
Acute polyneuropathy17.09.01.0030.000268%Not Available
Substance dependence19.07.06.0190.000447%Not Available
Axonal and demyelinating polyneuropathy17.09.03.025; 11.07.01.019; 10.04.10.0190.000179%Not Available
Behaviour disorder19.01.01.0050.000179%Not Available
Drug use disorder19.07.06.0120.001429%Not Available
Substance use disorder19.07.06.0200.000179%Not Available
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