Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Nitrous oxide
Drug ID BADD_D01580
Description Nitrous oxide, commonly known as "laughing gas", is a chemical compound with the chemical formula N2O. At room temperature, it is a colorless non-flammable gas, with a pleasant, slightly sweet odor and taste. It is used in surgery and dentistry for its anesthetic and analgesic effects. It is known as "laughing gas" due to the euphoric effects of inhaling it, a property that has led to its recreational use as an inhalant drug.
Indications and Usage
Marketing Status Prescription
ATC Code N01AX13
DrugBank ID DB06690
KEGG ID D00102
MeSH ID D009609
PubChem ID 948
TTD Drug ID D0O8DI
NDC Product Code 62273-005; 72223-001; 21220-122; 55037-301; 44517-020; 70151-004; 25373-703; 59579-004; 49575-003; 46123-007; 63978-201; 46362-003; 55050-0018; 46123-006; 18482-002; 44076-012; 48273-002; 54260-001; 20703-003; 10736-017; 10014-003; 10167-200; 10252-003; 52086-003; 62045-8333; 43621-003; 12213-593; 72276-002; 55404-002; 24312-003; 62097-0004; 51486-007; 52568-002; 12121-002; 73468-004; 72343-001; 42602-003; 34057-010; 53440-003; 11054-007; 25373-103; 67525-400; 54218-800; 67477-002; 17575-011; 52346-012; 25373-003; 50554-005; 53511-003
Synonyms Nitrous Oxide | Oxide, Nitrous | Laughing Gas | Gas, Laughing | Nitrogen Protoxide
Chemical Information
Molecular Formula N2O
CAS Registry Number 10024-97-2
SMILES [N-]=[N+]=O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Aggression19.05.01.0010.001182%Not Available
Agitation19.06.02.001; 17.02.05.0120.000788%
Amnesia19.20.01.001; 17.03.02.0010.000788%
Anaemia megaloblastic14.12.01.003; 01.03.02.003--Not Available
Arrhythmia02.03.02.001--Not Available
Asphyxia22.02.02.001; 12.01.08.0110.000925%Not Available
Aspiration22.02.07.0070.000206%
Ataxia17.02.02.001; 08.01.02.0040.001182%
Cardio-respiratory arrest22.02.06.007; 02.03.04.0020.000206%Not Available
Confusional state19.13.01.001; 17.02.03.0050.000788%
Cyanosis02.01.02.002; 24.03.01.007; 22.02.02.0070.000788%
Demyelination17.16.02.0010.000788%Not Available
Depression19.15.01.0010.001182%
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Drug abuse19.07.02.0100.005346%Not Available
Drug dependence19.07.02.0090.001182%Not Available
Euphoric mood19.04.02.006--
Feeling abnormal08.01.09.014--Not Available
Gait disturbance17.02.05.016; 08.01.02.0020.001182%
Headache17.14.01.001--
Hypoaesthesia17.02.06.0230.001970%Not Available
Hypotension24.06.03.002--
Hypoxia22.02.02.003--
Intracranial pressure increased17.07.02.002--Not Available
Laryngospasm22.04.02.0020.000788%
Leukopenia01.02.02.0010.000788%Not Available
Loss of consciousness17.02.04.0040.000206%Not Available
Memory impairment19.20.01.003; 17.03.02.0030.000788%
Mood swings19.04.03.0010.001182%Not Available
Muscle spasms15.05.03.0040.000788%
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