Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Nitroglycerin
Drug ID BADD_D01579
Description Nitroglycerin is a vasodilator drug used for the treatment of chest pain and high blood pressure.[T628,L4429] It was first approved in 2000 and is currently marketed by Pfizer, and other companies, depending on the dosage form.[T628,L4894] Nitroglycerin is available in various forms, including a spray form, sublingual tablet form, intravenous form, extended-release tablet form, and transdermal form. A less commonly known fact is that in addition to treating angina, nitroglycerin is also used in an ointment to treat the pain that accompanies anal fissures. The rectal ointment form of nitroglycerin was approved by the FDA in 1955.[L7096]
Indications and Usage For the prevention of angina
Marketing Status Prescription; Discontinued
ATC Code C01DA02; C05AE01
DrugBank ID DB00727
KEGG ID D00515
MeSH ID D005996
PubChem ID 4510
TTD Drug ID D07YDE
NDC Product Code 59762-4921; 51662-1340; 68071-2260; 28595-550; 60429-839; 0338-1051; 0378-9116; 52584-810; 47781-456; 0904-5495; 50090-4874; 0338-1047; 0220-2291; 43598-895; 0220-2287; 0281-0326; 63629-8829; 71872-7010; 51662-1282; 71872-7201; 70518-0545; 49483-223; 64117-543; 43598-896; 50742-516; 71205-225; 0378-9104; 0220-2283; 0071-0418; 76299-430; 63629-8830; 50742-517; 59762-0489; 49483-222; 0220-2279; 60429-840; 71872-7033; 0404-9928; 0378-9102; 50090-3266; 68428-407; 71205-482; 0220-2290; 50742-514; 0404-9929; 43598-435; 47781-457; 52584-418; 0517-4810; 0904-0643; 45802-210; 68071-4909; 42291-648; 28595-705; 0220-2286; 70518-0105; 50742-515; 50742-518; 0378-9112; 50742-513; 0338-1049; 43598-893; 70518-2910; 0220-2282; 0904-0647; 51662-1386; 68462-638; 28595-120; 68071-1330; 50090-0332; 50090-0133; 59762-3304; 51662-1351; 63187-884; 51662-1244; 68428-100; 68071-1720; 60429-841; 63629-8828; 0220-2293; 0071-0417; 0904-5497; 43598-437; 0904-5496; 43598-894; 68428-050; 47781-458; 0071-0419; 68462-639; 43598-436; 58914-301; 49483-221; 68462-640
Synonyms Nitroglycerin | Glyceryl Trinitrate | Trinitrate, Glyceryl | Nitrolan | Nitrospan | Nitrostat | Perlinganit | Nitrong | Susadrin | Sustac | Sustak | Sustonit | Transderm Nitro | Nitroglyn | Trinitrin | Trinitrolong | Anginine | Dynamite | Gilustenon | Nitrangin | Nitro-Bid | Nitro Bid | NitroBid | Nitro-Dur | Nitro Dur | NitroDur | Nitrocard | Nitroderm | Nitroderm TTS | Nitrol | Tridil
Chemical Information
Molecular Formula C3H5N3O9
CAS Registry Number 55-63-0
SMILES C(C(CO[N+](=O)[O-])O[N+](=O)[O-])O[N+](=O)[O-]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pruritus23.03.12.001--
Pulmonary oedema22.01.03.003; 02.05.02.0030.000846%
Pulse absent13.14.04.0050.000423%Not Available
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rash generalised23.03.13.002--Not Available
Rectal haemorrhage24.07.02.018; 07.12.03.0010.000282%
Reflexes abnormal17.02.01.0060.000282%Not Available
Respiratory failure22.02.06.002; 14.01.04.003--
Respiratory rate decreased13.15.01.003--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Seizure17.12.03.001--
Sensory disturbance17.02.07.0060.000282%Not Available
Shock24.06.02.0020.000423%Not Available
Sinus bradycardia02.03.03.0090.000423%
Skin discolouration23.03.03.0050.000423%Not Available
Skin disorder23.03.03.007--Not Available
Skin necrosis23.03.03.0110.000282%Not Available
Skin reaction23.03.03.013; 10.01.03.019--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Speech disorder22.02.05.034; 19.19.02.002; 17.02.08.0030.000282%Not Available
Stomatitis07.05.06.005--
Suffocation feeling22.02.08.0120.000282%Not Available
Swollen tongue23.04.01.014; 10.01.05.015; 07.14.02.0030.000423%Not Available
Syncope02.01.02.008; 24.06.02.012; 17.02.04.0080.002256%
Tachycardia02.03.02.0070.000564%Not Available
Tachypnoea22.02.01.014--Not Available
Tendonitis15.07.01.003; 12.01.07.0070.000282%Not Available
Thrombocytopenia01.08.01.0020.000705%Not Available
Thrombocytopenic purpura23.06.01.007; 01.08.01.0030.000564%Not Available
The 5th Page    First    Pre   5 6 7    Next   Last    Total 7 Pages