Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Nesiritide
Drug ID BADD_D01556
Description Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide.
Indications and Usage For the intravenous treatment of patients with acutely decompensated congestive heart failure who have dyspnea at rest or with minimal activity.
Marketing Status Prescription
ATC Code C01DX19
DrugBank ID DB04899
KEGG ID D05147
MeSH ID D020097
PubChem ID 53325981
TTD Drug ID D05GRY
NDC Product Code 35207-0009
Synonyms Natriuretic Peptide, Brain | Peptide, Brain Natriuretic | BNP-32 | BNP 32 | Brain Natriuretic Peptide-32 | Brain Natriuretic Peptide 32 | Natriuretic Peptide-32, Brain | Peptide-32, Brain Natriuretic | Natriuretic Factor-32 | Natriuretic Factor 32 | BNP Gene Product | Type-B Natriuretic Peptide | Natriuretic Peptide, Type-B | Type B Natriuretic Peptide | Natriuretic Peptide Type-B | Natriuretic Peptide Type B | Nesiritide | Brain Natriuretic Peptide | B-Type Natriuretic Peptide | Natriuretic Peptide, B-Type | Ventricular Natriuretic Peptide, B-type | Ventricular Natriuretic Peptide, B type | Natrecor
Chemical Information
Molecular Formula C143H244N50O42S4
CAS Registry Number 124584-08-3
SMILES CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O )NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)CC SC)CCCCN)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)CNC(=O)C(CO)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O )C(C(C)C)NC(=O)C(CCSC)NC(=O)C(CCCCN)NC(=O)C3CCCN3C(=O)C(CO)N)C(=O)NC(CCCCN)C(=O) NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC4=CN=CN4 )C(=O)O)CC(C)C)CO)CO)CO)CO
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Back pain15.03.04.005--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Hypoglycaemia14.06.03.001; 05.06.03.001--
Nausea07.01.07.001--
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Angiopathy24.03.02.007--Not Available
Infusion site extravasation12.07.05.008; 08.02.05.007--
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