Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Naratriptan hydrochloride
Drug ID BADD_D01536
Description Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.
Indications and Usage For the acute treatment of migraine attacks with or without aura in adults.
Marketing Status Prescription; Discontinued
ATC Code N02CC02
DrugBank ID DB00952
KEGG ID D00674
MeSH ID C106783
PubChem ID 60875
TTD Drug ID D0T3KI
NDC Product Code 53873-055; 55111-085; 0173-0562; 0173-0561; 62147-0195; 52482-011; 53873-056
Synonyms naratriptan | N-methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide | GR 85548A | naratriptan hydrochloride | N-methyl-3-(1-methyl-4-piperidyl)indole-5-ethanesulfonamide monohydrochloride | 1H-indole-5-ethanesulfonamide, N-methyl-3-(1-methyl-4-piperidinyl)-, monohydrochloride | Naramig | Amerge | Colatan
Chemical Information
Molecular Formula C17H26ClN3O2S
CAS Registry Number 143388-64-1
SMILES CNS(=O)(=O)CCC1=CC2=C(C=C1)NC=C2C3CCN(CC3)C.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Gastric ulcer07.04.03.002--
Gastritis07.08.02.001--
Gastrooesophageal reflux disease07.02.02.003--
Gastroenteritis11.01.07.004; 07.19.03.001--Not Available
Gastrointestinal pain07.01.05.005--
Glycosuria20.02.01.005--
Haemoglobin abnormal13.01.05.011--Not Available
Haemorrhoids24.10.02.002; 07.15.03.001--
Hallucination19.10.02.002--
Hostility19.05.01.003--Not Available
Hyperaesthesia17.02.06.004--Not Available
Hypercholesterolaemia14.08.01.001--Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypoaesthesia17.02.06.023--Not Available
Hypotension24.06.03.002--
Hypothyroidism14.11.01.012; 05.02.03.001--
Intestinal ischaemia24.04.08.001; 07.15.02.001--Not Available
Joint stiffness15.01.02.003--Not Available
Ketonuria20.02.01.009--Not Available
Labyrinthitis11.01.05.002; 04.04.03.001--Not Available
Libido decreased21.03.02.005; 19.08.03.001--
Liver function test abnormal13.03.01.013--Not Available
Malaise08.01.01.003--
Micturition urgency20.02.02.006--
Muscle contractions involuntary15.05.03.008; 17.05.03.001--Not Available
Muscle rigidity17.05.02.005; 15.05.04.001--Not Available
Muscle spasms15.05.03.004--
Muscle twitching15.05.03.005--Not Available
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