Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mometasone furoate
Drug ID BADD_D01491
Description Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than many other corticosteroids as well[A176906]. Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications[FDA Label][F4292,F4295].
Indications and Usage The inhaler is indicated for the maintenance treatment of asthma as prophylactic therapy. The nasal spray is indicated for the treatment of the nasal symptoms of seasonal allergic and perennial allergic rhinitis.
Marketing Status Prescription; Discontinued
ATC Code D07AC13; D07XC03; R01AD09; R03BA07
DrugBank ID DB14512
KEGG ID D00690
MeSH ID D000068656
PubChem ID 441336
TTD Drug ID D03HYX
NDC Product Code 63187-288; 78206-111; 63629-8681; 63190-0730; 10599-003; 63629-8686; 62991-3098; 16714-974; 68462-225; 0168-0270; 63629-8682; 60429-664; 63187-432; 11517-434; 71161-133; 64918-0330; 50090-1026; 71205-413; 51552-1510; 0713-0634; 0168-0272; 68462-385; 78206-115; 10695-111; 50909-5151; 78206-114; 0713-0635; 64918-0424; 13668-527; 78206-112; 70518-3244; 46439-8733; 63592-0387; 68462-192; 58175-1234; 52128-163; 0168-0271; 0713-0701; 63190-0340; 63592-0397; 45802-118; 60505-0830; 53002-8320; 70518-2883; 78206-113; 68071-4637; 63629-8683; 15308-0220; 51672-1311; 75895-0280; 63629-8685; 75895-0279; 11517-222; 0713-0726; 68071-4460; 68071-1538; 65089-0025; 11517-433; 22552-0002; 45802-119; 53104-7646; 51927-4506; 53002-8321; 45802-257; 0713-0727; 63629-8684; 38779-2413; 51672-1305; 51672-1315
Synonyms Mometasone Furoate | Furoate, Mometasone | Nasonex | Mometasone Furoate Monohydrate | Furoate Monohydrate, Mometasone | Monohydrate, Mometasone Furoate | Asmanex Twisthaler | Twisthaler, Asmanex | Asmanex | Rinelon | Elocon | Sch 32088 | Sch-32088 | Sch32088 | Mometasone
Chemical Information
Molecular Formula C27H30Cl2O6
CAS Registry Number 83919-23-7
SMILES CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)OC(=O)C5=CC=CO5)C)O)Cl)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Respiratory distress22.02.01.0120.000746%Not Available
Retching07.01.07.0020.000497%Not Available
Rhinitis22.07.03.006; 11.01.13.0040.000746%
Rhinitis allergic22.04.04.003; 10.01.04.0030.000497%
Rhinorrhoea22.02.05.0100.006464%
Rosacea23.02.08.001--Not Available
Salivary hypersecretion07.06.01.0090.000746%Not Available
Secondary adrenocortical insufficiency14.11.01.014; 05.01.02.003--Not Available
Sinus congestion22.04.06.0010.000497%Not Available
Sinus headache22.02.05.023; 17.14.01.0020.000746%
Sinusitis22.07.03.007; 11.01.13.0050.003481%
Skin atrophy23.01.05.001--
Skin depigmentation23.05.02.002--Not Available
Skin discolouration23.03.03.005--Not Available
Skin disorder23.03.03.007--Not Available
Skin exfoliation23.03.07.0030.000746%Not Available
Skin hypopigmentation23.05.02.003--
Skin irritation23.03.04.009--Not Available
Skin striae23.01.05.002--Not Available
Sneezing22.02.05.0110.003729%
Somnolence19.02.05.003; 17.02.04.006--
Speech disorder22.02.05.034; 19.19.02.002; 17.02.08.0030.000746%Not Available
Steroid withdrawal syndrome05.01.02.007; 19.04.02.014; 08.06.02.0130.002238%Not Available
Stress19.06.02.0040.000497%Not Available
Swelling08.01.03.015--Not Available
Swelling face23.04.01.018; 10.01.05.0180.001243%Not Available
Swollen tongue10.01.05.015; 07.14.02.003; 23.04.01.0140.000497%Not Available
Tachycardia02.03.02.007--Not Available
Telangiectasia24.03.03.003; 23.06.03.001--
Thirst14.03.02.007; 08.01.09.0210.000497%Not Available
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