Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mometasone furoate
Drug ID BADD_D01491
Description Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than many other corticosteroids as well[A176906]. Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications[FDA Label][F4292,F4295].
Indications and Usage The inhaler is indicated for the maintenance treatment of asthma as prophylactic therapy. The nasal spray is indicated for the treatment of the nasal symptoms of seasonal allergic and perennial allergic rhinitis.
Marketing Status Prescription; Discontinued
ATC Code D07AC13; D07XC03; R01AD09; R03BA07
DrugBank ID DB14512
KEGG ID D00690
MeSH ID D000068656
PubChem ID 441336
TTD Drug ID D03HYX
NDC Product Code 63187-288; 78206-111; 63629-8681; 63190-0730; 10599-003; 63629-8686; 62991-3098; 16714-974; 68462-225; 0168-0270; 63629-8682; 60429-664; 63187-432; 11517-434; 71161-133; 64918-0330; 50090-1026; 71205-413; 51552-1510; 0713-0634; 0168-0272; 68462-385; 78206-115; 10695-111; 50909-5151; 78206-114; 0713-0635; 64918-0424; 13668-527; 78206-112; 70518-3244; 46439-8733; 63592-0387; 68462-192; 58175-1234; 52128-163; 0168-0271; 0713-0701; 63190-0340; 63592-0397; 45802-118; 60505-0830; 53002-8320; 70518-2883; 78206-113; 68071-4637; 63629-8683; 15308-0220; 51672-1311; 75895-0280; 63629-8685; 75895-0279; 11517-222; 0713-0726; 68071-4460; 68071-1538; 65089-0025; 11517-433; 22552-0002; 45802-119; 53104-7646; 51927-4506; 53002-8321; 45802-257; 0713-0727; 63629-8684; 38779-2413; 51672-1305; 51672-1315
Synonyms Mometasone Furoate | Furoate, Mometasone | Nasonex | Mometasone Furoate Monohydrate | Furoate Monohydrate, Mometasone | Monohydrate, Mometasone Furoate | Asmanex Twisthaler | Twisthaler, Asmanex | Asmanex | Rinelon | Elocon | Sch 32088 | Sch-32088 | Sch32088 | Mometasone
Chemical Information
Molecular Formula C27H30Cl2O6
CAS Registry Number 83919-23-7
SMILES CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)OC(=O)C5=CC=CO5)C)O)Cl)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Chest discomfort22.02.08.001; 08.01.08.019; 02.02.02.0090.006215%Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.0110.001989%Not Available
Chills08.01.09.001; 15.05.03.0160.001243%
Choking22.02.05.0010.000746%Not Available
Chronic obstructive pulmonary disease22.03.01.0070.000497%Not Available
Condition aggravated08.01.03.004--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Conjunctivitis11.01.06.012; 06.04.01.002--
Cough22.02.03.0010.022624%
Cushing's syndrome24.08.04.001; 19.07.03.002; 14.11.01.007; 05.01.01.0010.000746%Not Available
Deafness04.02.01.0010.000497%Not Available
Death08.04.01.001--
Dehydration14.05.05.001--
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Dermatitis acneiform23.02.01.004--
Dermatitis bullous23.03.01.0020.000497%
Dermatitis contact12.03.01.040; 10.01.01.003; 23.03.04.004--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.0030.001492%Not Available
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.0070.004972%
Drug hypersensitivity10.01.01.001--Not Available
Dry eye06.08.02.0010.001243%
Dry mouth07.06.01.0020.001243%
Dry skin23.03.03.001--
Dry throat22.02.05.004; 07.06.01.0050.000746%Not Available
Dysgeusia17.02.07.003; 07.14.03.0010.004475%
Dysmenorrhoea21.01.01.002--
Dyspepsia07.01.02.001--
Dysphonia22.02.05.005; 19.19.03.002; 17.02.08.0040.004972%
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