Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Moexiprilat
Drug ID BADD_D01486
Description The active metabolite of the prodrug [Moexipril].
Indications and Usage Not Available
Marketing Status Not Available
ATC Code Not Available
DrugBank ID DB14210
KEGG ID Not Available
MeSH ID C059506
PubChem ID 55331
TTD Drug ID D0R6KV
NDC Product Code Not Available
Synonyms moexiprilat | 2-(2-(1-carboxy-3-phenylpropyl)amino-1-oxopropyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid | RS 10029 | RS-10029 | moexiprilat, (3S-(2(S*(R*)),3R*))-isomer | moexiprilat, (3R-(2(S*(S*)),3R*))-isomer | moexiprilat, (3S-(2(R*(S*)).3R*))-isomer
Chemical Information
Molecular Formula C25H30N2O7
CAS Registry Number 103775-14-0
SMILES CC(C(=O)N1CC2=CC(=C(C=C2CC1C(=O)O)OC)OC)NC(CCC3=CC=CC=C3)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.001--Not Available
Alopecia23.02.02.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Angina pectoris24.04.04.002; 02.02.02.002--
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Asthenia08.01.01.001--Not Available
Blood creatinine increased13.13.01.004--
Blood urea increased13.13.01.006--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Cerebrovascular accident17.08.01.007; 24.03.05.001--
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Constipation07.02.02.001--
Cough22.02.03.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness17.02.05.003; 24.06.02.007; 02.01.02.004--
Dry mouth07.06.01.002--
Dyspepsia07.01.02.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Gastrointestinal pain07.01.05.005--
Haemolytic anaemia01.06.03.002--Not Available
Headache17.14.01.001--
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