Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methyltestosterone
Drug ID BADD_D01438
Description A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US.
Indications and Usage Methyltestosterone is an anabolic steroid hormone used to treat men with a testosterone deficiency. It is also used in women to treat breast cancer, breast pain, swelling due to pregnancy, and with the addition of estrogen it can treat symptoms of menopause.
Marketing Status Prescription; Discontinued
ATC Code G03BA02; G03EK01
DrugBank ID DB06710
KEGG ID D00408
MeSH ID D008777
PubChem ID 6010
TTD Drug ID D0Z1XD
NDC Product Code 22552-0020; 0115-7037; 43647-345; 58159-070; 0115-1408; 51552-0031; 46439-8741; 70954-255; 60870-0232; 51927-1028
Synonyms Methyltestosterone | 17beta-Methyltestosterone | 17beta Methyltestosterone | 17 beta Methyltestosterone | 17 beta-Hydroxy-17-methyl-4-androsten-3-one | 17 beta Hydroxy 17 methyl 4 androsten 3 one | 17 beta-Methyltestosterone | 17beta-Hydroxy-17-methyl-4-androsten-3-one | 17beta Hydroxy 17 methyl 4 androsten 3 one | 17-Epimethyltestosterone | 17 Epimethyltestosterone | Android (Methyltestoterone) | Android-10 | Android 10 | Android-25 | Android 25 | Android-5 | Android 5 | Mesteron | Mesterone | Methitest | Oreton | Testoviron | Testred | Virilon | 17-alpha-Methyltestosterone | 17 alpha Methyltestosterone | 17alpha-Methyl-Testosterone | 17alpha Methyl Testosterone | 17alpha-Methyltestosterone | 17alpha Methyltestosterone | Metandren
Chemical Information
Molecular Formula C20H30O2
CAS Registry Number 58-18-4
SMILES CC12CCC(=O)C=C1CCC3C2CCC4(C3CCC4(C)O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acne23.02.01.001--Not Available
Alopecia23.02.02.001--
Amenorrhoea21.01.02.001; 05.05.01.002--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction10.01.07.003; 24.06.03.007--Not Available
Anxiety19.06.02.002--
Azoospermia21.03.03.001--
Blood calcium13.11.01.041--Not Available
Blood chloride13.11.01.042--Not Available
Blood cholesterol increased13.12.01.002--
Blood gonadotrophin decreased13.10.03.001--Not Available
Blood phosphorus13.11.01.023--Not Available
Blood potassium13.11.01.032--Not Available
Coagulopathy01.01.02.001--Not Available
Depression19.15.01.001--
Embolism venous24.01.01.003--Not Available
Enlarged clitoris21.08.02.001; 05.05.01.004--Not Available
Erection increased21.03.01.004; 19.08.04.002--Not Available
Fluid retention20.01.02.003; 14.05.06.002--Not Available
Gynaecomastia21.05.04.003; 05.05.02.003--
Haemoglobin13.01.05.018--Not Available
Headache17.14.01.001--
Hepatic neoplasm09.04.03.001; 16.07.03.001--Not Available
Hirsutism23.02.04.001; 05.05.01.005--
Jaundice cholestatic09.01.01.005--Not Available
Libido decreased21.03.02.005; 19.08.03.001--
Libido increased21.03.02.007; 19.08.03.002--
Liver function test abnormal13.03.01.013--Not Available
Menstruation irregular21.01.01.005; 05.05.01.008--
Nausea07.01.07.001--
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