Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methylergonovine
Drug ID BADD_D01428
Description A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)
Indications and Usage For the prevention and control of excessive bleeding following vaginal childbirth
Marketing Status Prescription; Discontinued
ATC Code G02AB01
DrugBank ID DB00353
KEGG ID D00680
MeSH ID D008755
PubChem ID 8226
TTD Drug ID D05AHE
NDC Product Code 69238-1605
Synonyms Methylergonovine | Methylergometrine | Methylergobasin | Methylergometrin | Methylergonovine Maleate | Methylergometrine Maleate | Methergine | Méthergin | Methergin
Chemical Information
Molecular Formula C20H25N3O2
CAS Registry Number 113-42-8
SMILES CCC(CO)NC(=O)C1CN(C2CC3=CNC4=CC=CC(=C34)C2=C1)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Acute myocardial infarction24.04.04.001; 02.02.02.001--Not Available
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Angina pectoris24.04.04.002; 02.02.02.002--
Arterial spasm24.04.02.011--Not Available
Atrioventricular block02.03.01.002--Not Available
Bradycardia02.03.02.002--Not Available
Cerebrovascular accident17.08.01.007; 24.03.05.001--
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.007--
Dyspnoea22.02.01.004; 02.01.03.002--
Gastrointestinal pain07.01.05.005--
Haematuria24.07.01.047; 20.02.01.006--
Hallucination19.10.02.002--
Headache17.14.01.001--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypertension24.08.02.001--
Hypotension24.06.03.002--
Muscle spasms15.05.03.004--
Nasal congestion22.04.04.001--
Nausea07.01.07.001--
Nervous system disorder17.02.10.001--Not Available
Palpitations02.01.02.003--
Paraesthesia17.02.06.005--
Rash23.03.13.001--Not Available
Seizure17.12.03.001--
Tachycardia02.03.02.007--Not Available
Thrombophlebitis24.01.02.001--Not Available
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