Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Methylergonovine
Drug ID BADD_D01428
Description A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)
Indications and Usage For the prevention and control of excessive bleeding following vaginal childbirth
Marketing Status approved
ATC Code G02AB01
DrugBank ID DB00353
KEGG ID D00680; D08207
MeSH ID D008755
PubChem ID 8226
TTD Drug ID D05AHE
NDC Product Code 69238-1605
UNII W53L6FE61V
Synonyms Methylergonovine | Methylergometrine | Methylergobasin | Methylergometrin | Methylergonovine Maleate | Methylergometrine Maleate | Methergine | Méthergin | Methergin
Chemical Information
Molecular Formula C20H25N3O2
CAS Registry Number 113-42-8
SMILES CCC(CO)NC(=O)C1CN(C2CC3=CNC4=CC=CC(=C34)C2=C1)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.0020.002243%
Acute myocardial infarction24.04.04.001; 02.02.02.001--Not Available
Agitation19.06.02.001; 17.02.05.0120.002243%
Anaphylactic shock10.01.07.002; 24.06.02.004--Not Available
Angina pectoris24.04.04.002; 02.02.02.002--
Apnoea22.02.01.0010.003365%
Areflexia17.02.01.0010.002243%Not Available
Arterial spasm24.04.02.011--Not Available
Arteriospasm coronary24.04.04.005; 02.02.02.005; 12.02.01.0310.002243%Not Available
Atrioventricular block02.03.01.002--Not Available
Bradycardia02.03.02.0020.003365%Not Available
Bronchospasm22.03.01.004; 10.01.03.0120.003365%
Cerebrovascular accident17.08.01.007; 24.03.05.001--
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Crying19.04.02.002; 12.02.11.001; 17.02.05.013; 08.01.03.0050.002243%Not Available
Cyanosis23.06.04.005; 02.11.04.004; 24.03.01.007; 22.02.02.0070.003365%
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.0010.002243%
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.0030.003365%
Drug ineffective08.06.01.0060.002243%Not Available
Dyspnoea02.11.05.003; 22.02.01.0040.004486%
Face oedema10.01.05.002; 08.01.07.003; 23.04.01.0040.002243%
Gastrointestinal pain07.01.05.005--
Haematuria21.10.01.018; 24.07.01.047; 20.02.01.006--
Hallucination19.10.04.003--
Headache17.14.01.0010.005608%
Hyperaesthesia23.03.03.080; 17.02.06.0040.002243%Not Available
Hypercapnia22.02.02.002; 14.01.04.0010.003365%Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypertension24.08.02.0010.002243%
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