Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methylene blue cation
Drug ID BADD_D01427
Description Not Available
Indications and Usage 6. Treatment of ifofosamide induced neurotoxicity.
Marketing Status Prescription
ATC Code V03AB17; V04CG05
DrugBank ID DB08167
KEGG ID C00220
MeSH ID D008751
PubChem ID 4139
TTD Drug ID D05CCT
NDC Product Code Not Available
Synonyms Methylene Blue | Blue, Methylene | Methylthioninium Chloride | Methylthionine Chloride | Swiss Blue | Blue, Swiss | Basic Blue 9 | Blue 9, Basic | Methylene Blue N | Blue N, Methylene | Chromosmon | Urolene Blue | Blue, Urolene
Chemical Information
Molecular Formula C16H18N3S+
CAS Registry Number 7060-82-4
SMILES CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Mucosal findings abnormalTumor necrosis factorP01375T20178Not Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agitation19.06.02.001; 17.02.05.012--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anxiety19.06.02.002--
Aphasia19.21.01.001; 17.02.03.001--
Arrhythmia02.03.02.001--Not Available
Body temperature increased13.15.01.001--Not Available
Chest pain02.02.02.011; 22.02.08.003; 08.01.08.002--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.007--
Dyspepsia07.01.02.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Dysuria20.02.02.002--
Extravasation08.01.03.008--Not Available
Eye disorder06.08.03.001--Not Available
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Glucose-6-phosphate dehydrogenase deficiency03.08.03.001; 01.06.05.001; 14.14.03.001--Not Available
Haemoglobin decreased13.01.05.003--Not Available
Haemolysis01.06.04.002--
Haemolytic anaemia01.06.03.002--Not Available
Headache17.14.01.001--
Hyperbilirubinaemia14.11.01.010; 09.01.01.003; 01.06.04.003--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypertension24.08.02.001--
Hypotension24.06.03.002--
Hypoxia22.02.02.003--
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