Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methsuximide
Drug ID BADD_D01422
Description Mesuximide (or methsuximide) is an anticonvulsant medication. It is sold by Pfizer under the name Petinutin.
Indications and Usage For the control of absence (petit mal) seizures that are refractory to other drugs.
Marketing Status Prescription
ATC Code N03AD03
DrugBank ID DB05246
KEGG ID D00404
MeSH ID C100286
PubChem ID 6476
TTD Drug ID D08EOD
NDC Product Code 0071-0525; 58159-063
Synonyms methsuximide | mesuximide | N,2-dimethyl-2-phenylsuccinimide | mesuximid | methsuximide, (+-)-isomer | Celontin | Petinutin | methsuximide, (+)-isomer | methsuximide, (-)-isomer
Chemical Information
Molecular Formula C12H13NO2
CAS Registry Number 77-41-8
SMILES CC1(CC(=O)N(C1=O)C)C2=CC=CC=C2
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Aggression19.05.01.001--Not Available
Ataxia17.02.02.001; 08.01.02.004--
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Coordination abnormal17.02.02.004--Not Available
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Eosinophilia01.02.04.001--
Erythema multiforme23.03.01.003; 10.01.03.015--
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Haematuria24.07.01.047; 20.02.01.006--
Hallucination, auditory19.10.02.003--Not Available
Headache17.14.01.001--
Hiccups22.02.04.002; 07.01.06.009--
Hyperaemia24.03.02.002--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Irritability19.04.02.013; 08.01.03.011--
Leukopenia01.02.02.001--Not Available
Mental impairment19.21.02.003; 17.03.03.002--Not Available
Monocytosis01.02.01.004--Not Available
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Pancytopenia01.03.03.003--Not Available
Periorbital oedema23.04.01.002; 10.01.05.010; 06.08.03.017--
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