Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Meperidine hydrochloride
Drug ID BADD_D01385
Description A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Indications and Usage Used to control moderate to severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AB02
DrugBank ID DB00454
KEGG ID D01383
MeSH ID D008614
PubChem ID 5750
TTD Drug ID D00UYE
NDC Product Code 0409-1178; 0409-1362; 0409-1255; 0641-6053; 0409-1179; 0409-1418; 51927-1018; 0641-6052; 0409-1180; 0641-6054; 0409-1181; 0409-1176; 0406-1585; 0054-3545; 42806-051; 49452-0031; 42806-050; 65392-0923; 30698-337; 30698-335
Synonyms Meperidine | Pethidine | Isonipecain | Dolsin | Dolosal | Dolin | Operidine EPJ-I | Operidine EPJ I | Dolantin | Dolargan | Meperidine Hydrochloride | Lidol | Lydol | Demerol | Dolcontral
Chemical Information
Molecular Formula C15H22ClNO2
CAS Registry Number 50-13-5
SMILES CCOC(=O)C1(CCN(CC1)C)C2=CC=CC=C2.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agitation19.06.02.001; 17.02.05.012--
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Asthenia08.01.01.001--Not Available
Biliary colic09.02.01.001--Not Available
Bradycardia02.03.02.002--Not Available
Cardiac arrest02.03.04.001--
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Delirium19.13.02.001--
Disorientation19.13.01.002; 17.02.05.015--Not Available
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.007--
Dry mouth07.06.01.002--
Dyskinesia17.01.02.006--
Dysphoria19.04.02.004--Not Available
Euphoric mood19.04.02.006--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Hallucination19.10.02.002--
Headache17.14.01.001--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypotension24.06.03.002--
Injection site urticaria12.07.03.029; 10.01.06.003; 08.02.03.029; 23.04.02.003--Not Available
Mood altered19.04.02.007--Not Available
Muscle twitching15.05.03.005--Not Available
Myoclonus17.02.05.008--Not Available
Nausea07.01.07.001--
Palpitations02.01.02.003--
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Respiratory arrest22.02.01.009--Not Available
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