Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Meloxicam
Drug ID BADD_D01374
Description Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis.[A190189] With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and intravenous formulations. It is a preferential COX-2 inhibitor, purportedly reducing the risk of adverse gastrointestinal tract effects, however, this is a topic of controversy.[A190198,A190201]
Indications and Usage For symptomatic treatment of arthritis and osteoarthritis.
Marketing Status Prescription; Discontinued
ATC Code M01AC06
DrugBank ID DB00814
KEGG ID D00969
MeSH ID D000077239
PubChem ID 54677470
TTD Drug ID D0G7FJ
NDC Product Code 61919-469; 38779-2746; 67296-1317; 29300-125; 68788-7904; 63629-2020; 71610-583; 0615-8124; 70518-1828; 65841-051; 43063-396; 43063-401; 72865-138; 69344-205; 80425-0043; 61919-434; 71610-580; 68071-4987; 71610-544; 42708-093; 65862-097; 70518-3023; 43063-395; 50090-5339; 51552-1377; 50436-1125; 17373-1157; 56125-750; 70954-077; 70859-007; 69344-206; 17373-1158; 72969-045; 60760-419; 60760-448; 43353-979; 80425-0045; 51869-0008; 76282-153; 65841-050; 70934-010; 60592-994; 72865-137; 59349-0003; 53002-1537; 50090-5861; 0615-8040; 53747-006; 68071-1919; 53069-0790; 50090-0986; 67296-1817; 50436-1124; 68071-3030; 71335-0406; 51407-610; 45865-360; 68382-050; 35356-808; 69097-159; 67296-0583; 54458-964; 50090-5340; 68180-502; 51407-611; 61442-126; 50090-0985; 61442-127; 71205-923; 43353-127; 68382-051; 80425-0041; 71518-001; 67296-0823; 68225-112; 16571-776; 50268-526; 51869-0007; 52119-003; 71610-542; 76282-152; 55289-618; 67296-1250; 49452-4402; 71335-1888; 68981-032; 60760-404; 70954-076; 42708-007; 68462-141; 68180-501; 65862-098; 70518-0039; 53002-2535; 71205-924; 54458-965; 80425-0042; 53104-7574; 68071-1993; 50090-4896; 70518-0200; 43353-038; 0395-8154; 68071-1994; 68071-2184; 60687-199; 53002-1535; 80425-0083; 65862-223; 68180-189; 68788-1701; 0597-0029; 70518-2631; 0597-0030; 64380-715; 68788-9418; 50268-525; 71610-380; 68462-140; 63629-3328; 29300-124; 69097-158; 76420-043; 51655-731; 63629-2019; 58118-1158; 68788-7726; 53002-2537; 71335-1956; 63629-7966; 64380-716; 71335-1618; 65841-004; 63187-082; 62938-0026; 63187-083; 71610-516; 68180-188; 16571-777; 70518-1299; 51927-0032; 70518-0031; 49999-869; 80425-0044; 76420-039; 51655-577; 63629-3248; 55289-272; 70518-0171; 22365-116; 58624-0430
Synonyms Meloxicam | Miloxicam | Parocin | Mobic | Mobicox | Mobec | Masflex | Movicox | Reumoxicam | Uticox | Movalis
Chemical Information
Molecular Formula C14H13N3O4S2
CAS Registry Number 71125-38-7
SMILES CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Small intestinal obstruction07.13.06.0010.000073%
Somnolence19.02.05.003; 17.02.04.006--
Stevens-Johnson syndrome11.07.01.005; 10.01.03.020; 23.03.01.007; 12.03.01.0140.000220%
Suicidal ideation19.12.01.003--
Suicide attempt19.12.01.004--
Swelling08.01.03.0150.000110%Not Available
Swelling face23.04.01.018; 10.01.05.0180.000110%Not Available
Syncope24.06.02.012; 17.02.04.008; 02.01.02.0080.000147%
Tachycardia02.03.02.007--Not Available
Thrombocytopenia01.08.01.0020.000330%Not Available
Thrombocytopenic purpura23.06.01.007; 01.08.01.0030.000073%Not Available
Tinnitus04.04.01.002; 17.04.07.004--
Tonsillitis11.01.13.006; 22.07.03.0080.000110%Not Available
Toxic epidermal necrolysis23.03.01.008; 12.03.01.015; 11.07.01.006; 10.01.01.0060.000019%
Transient ischaemic attack24.04.06.005; 17.08.04.0010.000147%
Tremor17.01.06.002--
Unresponsive to stimuli17.02.05.0310.000183%Not Available
Upper gastrointestinal haemorrhage24.07.02.024; 07.12.02.0060.000147%
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urinary retention20.02.02.011--
Urinary tract infection11.01.14.004; 20.08.02.001--
Urticaria23.04.02.001; 10.01.06.0010.000257%
Uveitis10.02.01.023; 06.04.03.0030.000073%
Vasculitis24.05.02.001; 10.02.02.006--
Vertigo17.02.12.002; 04.04.01.0030.000147%
Visual impairment06.02.06.0080.000110%Not Available
Vomiting07.01.07.003--
Weight decreased13.15.01.005--
Weight increased13.15.01.006--
Wheezing22.03.01.0090.000073%
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