Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Mefenamic acid
Drug ID BADD_D01368
Description A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Indications and Usage For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
Marketing Status approved
ATC Code M01AG01
DrugBank ID DB00784
KEGG ID D00151
MeSH ID D008528
PubChem ID 4044
TTD Drug ID D05FTJ
NDC Product Code 80425-0306; 51552-1367; 58747-0601; 62250-677; 62350-0015; 49452-4398; 52935-0008; 51927-4457; 0276-0509; 38779-0669; 42571-258; 68180-185; 22365-117
UNII 367589PJ2C
Synonyms Mefenamic Acid | Acid, Mefenamic | Mefenaminic Acid | Pontal | Contraflam | Coslan | Parkemed | Ponstan Forte | Ponsyl | Dysman | Mefac | Mefacit | Nu-Mefenamic | Nu Mefenamic | Pinalgesic | PMS-Mefenamic Acid | PMS Mefenamic Acid | Ponalar | Ponalgic | Ponmel | Ponstan | Ponstel | Mefic | Apo-Mefenamic | Apo Mefenamic
Chemical Information
Molecular Formula C15H15NO2
CAS Registry Number 61-68-7
SMILES CC1=C(C(=CC=C1)NC2=CC=CC=C2C(=O)O)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Renal papillary necrosis20.01.07.002; 14.07.02.001; 05.07.02.001--Not Available
Respiratory depression22.02.01.010; 17.02.05.047--Not Available
Seizure17.12.03.0010.010409%
Sepsis11.01.11.003--
Shock24.06.02.002--Not Available
Skin disorder23.03.03.007--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Steatorrhoea07.17.01.002--Not Available
Stevens-Johnson syndrome10.01.01.045; 23.03.01.007; 12.03.01.014; 11.07.01.005--
Stomatitis07.05.06.005--
Syncope02.11.04.015; 24.06.02.012; 17.02.04.008--
Tachycardia02.03.02.0070.002974%Not Available
Tension19.06.02.005--Not Available
Thrombocytopenia01.08.01.002--Not Available
Tinnitus04.04.01.002; 17.04.07.004--
Toxic epidermal necrolysis11.07.01.006; 23.03.01.008; 10.01.01.006; 12.03.01.015--
Tremor17.01.06.002--
Ulcer08.03.06.001--Not Available
Urethral disorder20.07.01.002--Not Available
Urinary tract disorder20.08.01.001--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vascular purpura24.07.06.011; 23.06.01.008; 01.01.04.007--Not Available
Vasculitis24.12.04.027; 10.02.02.006--
Vertigo04.04.01.003; 17.02.12.002--
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.0030.002974%
Tubulointerstitial nephritis20.05.02.002--Not Available
Hypoacusis04.02.01.006--
Platelet aggregation inhibition01.08.03.002--Not Available
Acute coronary syndrome24.04.04.011; 02.02.02.015--Not Available
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