Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mebeverine
Drug ID BADD_D01354
Description Mebeverine has been investigated for the treatment of Irritable Bowel Syndrome and Post-cholecystectomy Gastrointestinal Spasms.
Indications and Usage
Marketing Status Not Available
ATC Code A03AA04
DrugBank ID DB12554
KEGG ID D08160
MeSH ID C005096
PubChem ID 4031
TTD Drug ID D0VU8Q
NDC Product Code Not Available
Synonyms mebeverine | 4-(ethyl-(4-methoxy-alpha-methylphenethyl)aminobutyl) veratrate | duspatalin | spasmotalin | mebeverine hydrochloride
Chemical Information
Molecular Formula C25H35NO5
CAS Registry Number 3625-06-7
SMILES CCN(CCCCOC(=O)C1=CC(=C(C=C1)OC)OC)C(C)CC2=CC=C(C=C2)OC
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic shock10.01.07.002; 24.06.02.004--Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Dermatitis23.03.04.002--Not Available
Discomfort08.01.08.003--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dyspepsia07.01.02.001--
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003--
Feeling abnormal08.01.09.014--Not Available
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Immune system disorder10.02.01.001--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Malaise08.01.01.003--
Rash23.03.13.001--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Decreased appetite14.03.01.005; 08.01.09.028--
Ill-defined disorder08.01.03.049--Not Available
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