Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mafenide acetate
Drug ID BADD_D01338
Description Mafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns.
Indications and Usage Mafenide is indicated in the treatment of severe burns.
Marketing Status Prescription
ATC Code D06BA03
DrugBank ID DB06795
KEGG ID D01166
MeSH ID D008272
PubChem ID 25590
TTD Drug ID D0K1QD
NDC Product Code 49884-902; 51079-623; 65392-2801; 42973-157; 51079-624; 16571-723; 55718-137; 65015-889; 50742-310
Synonyms Mafenide | Maphenid | Mafenide Acetate | Sulfamylon | Marfanil | Napaltan | 4-Homosulfanilamide | 4 Homosulfanilamide | Sulfabenzamine | Bensulfamide | Mafylon
Chemical Information
Molecular Formula C9H14N2O4S
CAS Registry Number 13009-99-9
SMILES CC(=O)O.C1=CC(=CC=C1CN)S(=O)(=O)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acidosis14.01.03.002--
Application site pain12.07.01.004; 08.02.01.004--Not Available
Blister23.03.01.001; 12.01.06.002--Not Available
Blood chloride increased13.11.01.005--Not Available
Blood gases abnormal13.02.01.007--Not Available
Death08.04.01.001--
Diarrhoea07.02.01.001--
Disseminated intravascular coagulation24.01.01.010; 01.01.02.002--
Eosinophilia01.02.04.001--
Erythema23.03.06.001--Not Available
Face oedema10.01.05.002; 08.01.07.003; 23.04.01.004--
Haemolytic anaemia01.06.03.002--Not Available
Hyperventilation22.02.01.006; 19.01.02.004--Not Available
Porphyria acute17.19.01.001; 14.14.01.002; 09.01.10.001; 03.08.01.002; 19.07.03.003--Not Available
Pruritus23.03.12.001--
Swelling08.01.03.015--Not Available
Tachypnoea22.02.01.014--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Excoriation23.03.11.003; 12.01.06.007--Not Available
Skin burning sensation23.03.03.021; 17.02.06.009--Not Available
Skin haemorrhage24.07.06.009; 23.06.07.001--Not Available
Bone marrow failure01.03.03.005--
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