Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lurasidone
Drug ID BADD_D01330
Description Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Indications and Usage Treatment of schizophrenia.
Marketing Status Prescription
ATC Code N05AE05
DrugBank ID DB08815
KEGG ID D04820
MeSH ID D000069056
PubChem ID 213046
TTD Drug ID D01QGX
NDC Product Code 50370-0036
Synonyms Lurasidone Hydrochloride | Hydrochloride, Lurasidone | Lurasidone HCl | HCl, Lurasidone | SM 13496 | 13496, SM | SM13496 | SM-13,496 | SM 13,496 | SM13,496 | SM-13496 | Lurasidone | N-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl)-1-cyclohexylmethyl)-2,3-bicyclo(2.2.1)heptanedicarboximide | Latuda
Chemical Information
Molecular Formula C28H36N4O2S
CAS Registry Number 367514-87-2
SMILES C1CCC(C(C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)C6C7CCC(C7)C6C5=O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Neuroleptic malignant syndrome17.05.02.003; 15.05.04.015; 12.03.01.003; 08.05.01.0050.001592%Not Available
Neutropenia01.02.03.0040.003981%Not Available
Neutrophil count increased13.01.06.0110.001592%Not Available
Nightmare19.02.03.003--Not Available
Oculogyric crisis17.01.03.002; 06.05.02.0020.002389%Not Available
Oedema14.05.06.010; 08.01.07.0060.001592%Not Available
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.0070.003185%
Orthostatic hypotension24.06.03.004; 17.05.01.0200.001592%Not Available
Osteoarthritis15.01.04.001--Not Available
Pain in extremity15.03.04.010--
Pancreatitis07.18.01.0010.002389%
Panic attack19.06.04.0010.001592%Not Available
Paraesthesia17.02.06.005--
Paranoia19.05.01.0050.002389%Not Available
Parkinsonism17.01.05.003--Not Available
Pharyngeal oedema23.04.01.016; 22.04.05.003; 10.01.05.0160.002389%Not Available
Pneumonia11.01.09.003; 22.07.01.003--Not Available
Pregnancy18.08.02.004--Not Available
Premature baby18.04.02.0010.002389%Not Available
Pruritus23.03.12.001--
Psychomotor retardation19.15.02.002--Not Available
Pulmonary embolism24.01.06.001; 22.06.02.001--Not Available
Pyrexia08.05.02.003--
Rash23.03.13.0010.010351%Not Available
Rash generalised23.03.13.0020.002389%Not Available
Rash pruritic23.03.12.0020.002389%Not Available
Renal failure20.01.03.005--Not Available
Respiratory distress22.02.01.0120.002389%Not Available
Restlessness19.11.02.002; 17.02.05.0210.003981%
Rhabdomyolysis15.05.05.0020.002389%
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