Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lurasidone
Drug ID BADD_D01330
Description Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Indications and Usage Treatment of schizophrenia.
Marketing Status approved; investigational
ATC Code N05AE05
DrugBank ID DB08815
KEGG ID D04820
MeSH ID D000069056
PubChem ID 213046
TTD Drug ID D01QGX
NDC Product Code 50370-0036
UNII 22IC88528T
Synonyms Lurasidone Hydrochloride | Hydrochloride, Lurasidone | Lurasidone HCl | HCl, Lurasidone | SM 13496 | 13496, SM | SM13496 | SM-13,496 | SM 13,496 | SM13,496 | SM-13496 | Lurasidone | N-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl)-1-cyclohexylmethyl)-2,3-bicyclo(2.2.1)heptanedicarboximide | Latuda
Chemical Information
Molecular Formula C28H36N4O2S
CAS Registry Number 367514-87-2
SMILES C1CCC(C(C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)C6C7CCC(C7)C6C5=O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Muscle spasms15.05.03.004--
Muscle twitching15.05.03.0050.002722%Not Available
Myalgia15.05.02.001--
Nasopharyngitis22.07.03.002; 11.01.13.002--Not Available
Nausea07.01.07.0010.030693%
Neck pain15.03.04.009--
Nervous system disorder17.02.10.001--Not Available
Nervousness19.06.02.0030.000721%Not Available
Neuroleptic malignant syndrome17.05.02.003; 15.05.04.015; 12.03.01.003; 08.05.01.0050.000656%Not Available
Neutropenia01.02.03.004--Not Available
Nightmare19.02.03.0030.002000%Not Available
Obsessive-compulsive disorder19.06.05.0020.001279%Not Available
Oculogyric crisis17.01.03.002; 06.05.02.0020.000984%Not Available
Oedema14.05.06.010; 08.01.07.0060.001049%Not Available
Oedema peripheral08.01.07.007; 02.05.04.007; 14.05.06.0110.003279%
Orthostatic hypotension24.06.03.004; 17.05.01.0200.001443%Not Available
Osteoarthritis15.01.04.001--Not Available
Pancreatitis07.18.01.0010.000656%
Panic attack19.06.04.0010.001836%Not Available
Paranoia19.05.01.0050.001049%Not Available
Parkinsonism17.01.05.0030.000492%Not Available
Pharyngeal oedema23.04.01.016; 22.04.05.003; 10.01.05.0160.001279%Not Available
Pollakiuria20.02.02.0070.000721%
Polymenorrhoea21.01.03.0030.001115%Not Available
Pregnancy18.08.02.0040.001804%Not Available
Premature baby18.04.02.0010.000492%Not Available
Protrusion tongue17.02.05.037; 07.14.02.0020.000328%Not Available
Pruritus23.03.12.001--
Psychomotor hyperactivity19.11.02.003; 17.01.02.0110.001672%Not Available
Psychomotor retardation19.15.02.002--Not Available
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