| Drug Name |
Losartan potassium |
| Drug ID |
BADD_D01323 |
| Description |
Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension.[L7423] Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough.[L7423] When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo or [hydrochlorothiazide].[L7423] Losartan is available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and hydrochlorothiazide.[L7423,L7426] Patients taking losartan should have their renal function and potassium levels monitored.[L7423] Losartan was granted FDA approval on 14 April 1995.[L7423] |
| Indications and Usage |
May be used as a first line agent to treat uncomplicated hypertension, isolated systolic hypertension and left ventricular hypertrophy. May be used as a first line agent to delay progression of diabetic nephropathy. Losartan may be also used as a second line agent in the treatment of congestive heart failure, systolic dysfunction, myocardial infarction and coronary artery disease in those intolerant of ACE inhibitors. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
C09CA01 |
| DrugBank ID |
DB00678
|
| KEGG ID |
D00357
|
| MeSH ID |
D019808
|
| PubChem ID |
9847164
|
| TTD Drug ID |
D0DD0K
|
| NDC Product Code |
70518-0245; 46708-447; 68071-5184; 73377-096; 43063-854; 17511-127; 71610-417; 68071-5146; 50090-4048; 50090-4914; 62332-028; 68071-5209; 43063-881; 65015-691; 70934-932; 68645-586; 68071-5041; 63187-708; 68071-5183; 43547-361; 42571-110; 53747-023; 71610-065; 57237-206; 50090-2622; 72789-165; 68071-4141; 72789-029; 68071-5181; 72865-142; 71335-1102; 43063-347; 72865-141; 50090-3409; 31722-700; 70518-0718; 63187-071; 71335-1174; 68071-4454; 65862-202; 68071-5147; 71335-0698; 69766-098; 68084-347; 0904-7049; 13107-197; 70518-3282; 53002-3643; 64380-934; 68071-1518; 68071-1515; 55154-2327; 71205-226; 42708-152; 68071-4414; 63415-0057; 0054-0125; 68071-3301; 55700-769; 71610-241; 71205-069; 64220-164; 70518-2132; 72789-163; 59746-335; 70518-0087; 46708-874; 42571-112; 68071-5159; 50090-3403; 66639-001; 53002-2624; 71205-598; 72789-164; 63187-072; 68788-7736; 65841-730; 43547-362; 55154-7631; 68554-0008; 0054-0123; 0615-7958; 50090-5406; 65862-201; 68071-2216; 68071-2205; 70934-239; 55154-2326; 51927-5093; 71335-1582; 68071-2203; 43063-955; 53002-3638; 50090-5626; 71610-083; 60312-0951; 65862-203; 72189-082; 42708-113; 63187-391; 68071-4399; 72789-179; 72789-044; 55154-6643; 71610-282; 71610-224; 68788-7914; 62207-007; 71610-465; 43063-954; 59746-333; 71335-1136; 31722-701; 50090-4252; 71610-207; 71610-439; 68382-137; 53002-1638; 55154-7285; 13668-409; 50090-2882; 42708-055; 50268-505; 55111-083; 70934-781; 68788-7167; 63739-698; 68071-4413; 68071-5034; 71335-1235; 68071-5040; 60312-0960; 57237-205; 71335-0262; 51655-418; 0615-7960; 62332-029; 71610-370; 71335-1817; 68071-1517; 63187-296; 0615-7959; 71610-230; 59746-334; 53002-2638; 63187-830; 0904-7048; 68071-3216; 64380-933; 71335-1345; 71610-415; 70518-1319; 50090-4255; 71205-281; 53002-2643; 50090-5337; 0904-7047; 53002-1624; 68071-5114; 29300-145; 66577-028; 71610-082; 55154-2089; 42291-422; 33342-046; 78206-123; 71205-102; 42291-423; 68084-346; 50090-2656; 46708-445; 71610-155; 68071-4380; 65841-729; 53002-4643; 71610-009; 71205-212; 65372-1122; 50268-506; 68071-4471; 63187-357; 63629-2427; 43547-360; 63629-2428; 72189-096; 13668-113; 42291-424; 68788-7570; 50090-4910; 63629-8085; 68180-378; 71610-418; 70518-2786; 68180-376; 61919-864; 53002-4624; 42571-111; 42708-125; 50090-5480; 68071-4891; 68180-377; 60760-125; 50268-504; 13107-195; 50090-4489; 50090-4712; 68788-9712; 57237-204; 68071-1684; 60760-786; 53002-1643; 68071-2344; 65841-731; 60312-0952; 15894-0028; 71335-0181; 50090-5338; 42708-151; 46708-446; 68554-0098; 70518-3305; 78206-122; 63187-808; 68788-9305; 71335-1221; 50090-4645; 63739-673; 68071-5095; 71335-0972; 68071-4823; 31722-702; 72865-143; 71335-1580; 0054-0124; 71335-1644; 68788-7664; 78206-121; 63629-2426; 72189-317; 72189-100; 55154-4783; 68084-348; 53002-5624; 71610-260; 68382-136; 63629-4238; 68382-135; 71335-1328; 55154-2333; 72189-303; 45865-687; 13668-115; 68788-7737; 68071-5212; 70518-2530; 33342-045; 33342-044; 68788-7665; 50090-5481; 71610-466; 29300-146; 13107-196; 61919-877; 71610-171; 68071-5175; 29300-144; 65862-428; 68071-4932; 64380-935; 63739-686; 62332-027; 71205-194; 71610-440 |
| Synonyms |
Losartan | 2-Butyl-4-chloro-1-((2'-(1H-etrazol-5-yl) (1,1'-biphenyl)-4-yl)methyl)-1H-imidazole-5-methanol | DuP-753 | DuP 753 | DuP753 | MK-954 | MK 954 | MK954 | Cozaar | Losartan Potassium | Potassium, Losartan | Losartan Monopotassium Salt | Monopotassium Salt, Losartan | Salt, Losartan Monopotassium |
