| Pharmaceutical Information |
| Drug Name |
Loperamide cation |
| Drug ID |
BADD_D01314 |
| Description |
One of the long-acting synthetic antidiarrheals; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally. |
| Indications and Usage |
For the control and symptomatic relief of acute nonspecific diarrhea and of chronic diarrhea associated with inflammatory bowel disease or gastroenteritis. Also used for reducing the volume of discharge from ileostomies. |
| Marketing Status |
Prescription; OTC; Discontinued |
| ATC Code |
A07DA03 |
| DrugBank ID |
DB00836
|
| KEGG ID |
D00729
|
| MeSH ID |
D008139
|
| PubChem ID |
3954
|
| TTD Drug ID |
D0CS2F
|
| NDC Product Code |
Not Available |
| Synonyms |
Loperamide | R-18553 | R 18553 | R18553 | Imodium | Loperamide Hydrochloride | Hydrochloride, Loperamide | Loperamide Monohydrochloride | Monohydrochloride, Loperamide |
|
| Chemical Information |
| Molecular Formula |
C29H34ClN2O2+ |
| CAS Registry Number |
53179-11-6 |
| SMILES |
CN(C)C(=O)C(CC[NH+]1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4 |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
|
