Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Lithium carbonate
Drug ID BADD_D01303
Description Lithium has been used to treat manic episodes since the 19th century[A176642]. Though it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843]. Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label].
Indications and Usage Lithium is used as a mood stabilizer, and is indicated for the treatment of manic episodes and maintenance of bipolar disorder[FDA Label].
Marketing Status approved
ATC Code Not Available
DrugBank ID DB14509
KEGG ID D00801
MeSH ID D016651
PubChem ID 11125
TTD Drug ID D04UUH
NDC Product Code 31722-546; 62332-148; 62756-430; 63187-304; 64980-205; 68462-221; 70518-0608; 70518-2312; 70518-2345; 70518-3565; 72789-171; 72789-172; 31722-544; 62332-014; 68071-2714; 0054-8531; 46708-303; 55154-4920; 63629-1916; 0378-1450; 70518-0668; 70518-3681; 0054-4527; 62332-013; 68462-220; 68462-222; 68462-223; 70518-0437; 70518-2699; 68084-655; 70518-1434; 0054-2531; 71335-0120; 0054-8528; 0615-8302; 50090-3917; 58118-0545; 0054-8526; 51079-142; 63629-1917; 68462-224; 71610-557; 72789-173; 39345-5104; 46708-305; 0378-1300; 64980-278; 70518-1753; 70518-2086; 0054-2526; 31722-545; 50090-1470; 62332-015; 62559-280; 0054-0020; 68428-481; 0054-2527; 72789-174; 82388-001; 46708-148; 50090-6052; 64117-256; 0054-0021; 68084-640; 70518-0904; 70518-1481; 0054-8527; 66039-947; 73309-248; 23155-763; 42291-496; 43063-901; 46708-304; 51079-180
UNII 2BMD2GNA4V
Synonyms Lithium Carbonate | Carbonate, Lithium | Dilithium Carbonate | Carbonate, Dilithium | Lithane | Lithium Bicarbonate | Bicarbonate, Lithium | Lithobid | Lithonate | CP-15,467-61 | CP 15,467 61 | CP15,46761 | Micalith | NSC-16895 | NSC 16895 | NSC16895 | Priadel | Quilinorm-retard | Quilinorm retard | Quilinormretard | Eskalith | Lithotabs
Chemical Information
Molecular Formula CLi2O3
CAS Registry Number 554-13-2
SMILES [Li+].[Li+].C(=O)([O-])[O-]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Rhabdomyolysis15.05.05.0020.000803%
Salivary gland enlargement07.06.03.002--Not Available
Salivary hypersecretion07.06.01.0090.000803%Not Available
Schizoaffective disorder19.03.02.0020.000535%Not Available
Seizure17.12.03.0010.001874%
Serotonin syndrome17.05.02.004; 15.05.04.016; 12.03.01.0410.000535%Not Available
Sexual dysfunction21.03.02.003; 19.08.05.002--Not Available
Shock24.06.02.002--Not Available
Sinus arrhythmia02.03.03.008--Not Available
Sinus bradycardia02.03.03.0090.001071%
Skin disorder23.03.03.007--Not Available
Skin ulcer24.04.03.007; 23.07.03.003--
Sluggishness08.01.01.004--Not Available
Somnolence19.02.05.003; 17.02.04.0060.004604%
Speech disorder22.12.03.027; 19.19.02.002; 17.02.08.0030.000803%Not Available
Status epilepticus17.12.03.0050.001606%Not Available
Stupor19.02.05.004; 17.02.04.007--Not Available
Suicide attempt19.12.01.0040.003212%
Swelling08.01.03.015--Not Available
Syncope02.11.04.015; 24.06.02.012; 17.02.04.008--
Tachycardia02.03.02.0070.001071%Not Available
Tardive dyskinesia17.01.02.0120.000535%Not Available
Testicular pain21.13.01.0050.000535%
Therapeutic response decreased08.06.01.016--Not Available
Thinking abnormal19.10.03.001; 17.02.05.0230.000535%Not Available
Thirst14.03.02.007; 08.01.09.021--Not Available
Thyroid disorder05.02.01.0020.001446%Not Available
Thyroiditis05.02.04.0010.001338%Not Available
Thyrotoxic crisis19.07.03.006; 14.11.01.016; 06.09.04.004; 05.02.02.0040.001606%Not Available
Tic19.11.04.001; 17.02.05.024--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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