Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lithium carbonate
Drug ID BADD_D01303
Description Lithium has been used to treat manic episodes since the 19th century[A176642]. Though it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843]. Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label].
Indications and Usage Lithium is used as a mood stabilizer, and is indicated for the treatment of manic episodes and maintenance of bipolar disorder[FDA Label].
Marketing Status approved
ATC Code Not Available
DrugBank ID DB14509
KEGG ID D00801
MeSH ID D016651
PubChem ID 11125
TTD Drug ID D04UUH
NDC Product Code 31722-546; 62332-148; 62756-430; 63187-304; 64980-205; 68462-221; 70518-0608; 70518-2312; 70518-2345; 70518-3565; 72789-171; 72789-172; 31722-544; 62332-014; 68071-2714; 0054-8531; 46708-303; 55154-4920; 63629-1916; 0378-1450; 70518-0668; 70518-3681; 0054-4527; 62332-013; 68462-220; 68462-222; 68462-223; 70518-0437; 70518-2699; 68084-655; 70518-1434; 0054-2531; 71335-0120; 0054-8528; 0615-8302; 50090-3917; 58118-0545; 0054-8526; 51079-142; 63629-1917; 68462-224; 71610-557; 72789-173; 39345-5104; 46708-305; 0378-1300; 64980-278; 70518-1753; 70518-2086; 0054-2526; 31722-545; 50090-1470; 62332-015; 62559-280; 0054-0020; 68428-481; 0054-2527; 72789-174; 82388-001; 46708-148; 50090-6052; 64117-256; 0054-0021; 68084-640; 70518-0904; 70518-1481; 0054-8527; 66039-947; 73309-248; 23155-763; 42291-496; 43063-901; 46708-304; 51079-180
UNII 2BMD2GNA4V
Synonyms Lithium Carbonate | Carbonate, Lithium | Dilithium Carbonate | Carbonate, Dilithium | Lithane | Lithium Bicarbonate | Bicarbonate, Lithium | Lithobid | Lithonate | CP-15,467-61 | CP 15,467 61 | CP15,46761 | Micalith | NSC-16895 | NSC 16895 | NSC16895 | Priadel | Quilinorm-retard | Quilinorm retard | Quilinormretard | Eskalith | Lithotabs
Chemical Information
Molecular Formula CLi2O3
CAS Registry Number 554-13-2
SMILES [Li+].[Li+].C(=O)([O-])[O-]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Memory impairment19.20.01.003; 17.03.02.003--
Mental disability26.01.01.001--Not Available
Mental impairment19.21.02.003; 17.03.03.0020.000535%Not Available
Metabolic acidosis14.01.01.0030.001606%Not Available
Mood swings19.04.03.0010.000535%Not Available
Mucosal dryness08.01.06.0010.000535%Not Available
Muscle contractions involuntary17.05.03.001; 15.05.03.008--Not Available
Muscle rigidity17.05.02.005; 15.05.04.0010.000803%Not Available
Muscle spasms15.05.03.004--
Muscle twitching15.05.03.005--Not Available
Muscular weakness17.05.03.005; 15.05.06.0010.001071%
Myasthenia gravis17.05.04.001; 15.05.08.001; 10.04.05.001--
Myocarditis02.04.03.0010.000535%
Myoclonus17.02.05.0080.003587%Not Available
Myxoedema23.07.04.007; 05.02.03.002--Not Available
Nail discolouration23.02.05.001--
Nausea07.01.07.001--
Neoplasm malignant16.16.01.0010.000535%Not Available
Nephrogenic diabetes insipidus20.05.03.010; 14.05.07.0020.010654%Not Available
Nephrolithiasis20.04.01.0020.000535%
Nephropathy20.05.03.0010.008298%Not Available
Nephropathy toxic12.03.01.010; 20.05.03.0020.004551%Not Available
Nervous system disorder17.02.10.0010.001606%Not Available
Neuroleptic malignant syndrome17.05.02.003; 15.05.04.015; 12.03.01.003; 08.05.01.0050.000535%Not Available
Neurotoxicity17.02.10.002; 12.03.01.0110.003748%Not Available
Nodal rhythm02.03.03.0210.000535%Not Available
Nystagmus17.02.02.006; 06.05.02.0060.000803%
Oedema14.05.06.010; 08.01.07.006--Not Available
Oedema peripheral08.01.07.007; 02.05.04.007; 14.05.06.011--
Oliguria20.01.03.004--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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