Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lincomycin hydrochloride
Drug ID BADD_D01293
Description Lincomycin is a lincosamide antibiotic first isolated from the soil bacterium _Streptomyces lincolnensis_ in Lincoln, Nebraska.[A190621] Clinical use of lincomycin has largely been superseded by its semisynthetic derivative [clindamycin] due to its higher efficacy and a wider range of susceptible organisms, though lincomycin remains in use.[A190657, A190621] Lincomycin was approved by the FDA on December 29, 1964.[L33214]
Indications and Usage Lincomycin is an antibiotic used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.
Marketing Status Prescription; Discontinued
ATC Code J01FF02
DrugBank ID DB01627
KEGG ID D02346
MeSH ID D008034
PubChem ID 64710
TTD Drug ID D0Q0EX
NDC Product Code 42881-0001; 39822-0350; 39822-0353; 52584-353; 0009-0555; 50090-4533; 20076-0404; 0404-9901; 51927-3177; 0009-5168; 43781-2301; 55043-001
Synonyms Lincomycin | Lincomycin A | Lincolnensin | Lincomycin Hydrochloride | Lincomycin Monohydrochloride | Lincomycin, (L-threo)-Isomer | Epilincomycin | Lincomycin Monohydrochloride, (L-threo)-Isomer | Lincomycin Monohydrochloride, Hemihydrate | Hemihydrate Lincomycin Monohydrochloride | Lincomycin, (2S-cis)-Isomer | Lincocin | Lincomycin Monohydrochloride, (2S-cis)-Isomer
Chemical Information
Molecular Formula C18H35ClN2O6S
CAS Registry Number 859-18-7
SMILES CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Induration08.01.03.020--Not Available
Renal impairment20.01.03.010--Not Available
Anal pruritus07.03.03.002--Not Available
Anorectal discomfort07.03.03.003--Not Available
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