Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Levobunolol
Drug ID BADD_D01267
Description A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.
Indications and Usage For lowering intraocular pressure (IOP) and may be used in patients with chronic open-angle glaucoma or ocular hypertension.
Marketing Status Prescription; Discontinued
ATC Code S01ED03
DrugBank ID DB01210
KEGG ID D08115
MeSH ID D002040
PubChem ID 39468
TTD Drug ID D00IUG
NDC Product Code Not Available
Synonyms Levobunolol | Apo-Levobunolol | Apo Levobunolol | ApoLevobunolol | Betagan | Levobunolol Hydrochloride | Novo-Levobunolol | Novo Levobunolol | NovoLevobunolol | W-7000A | W 7000A | W7000A | ratio-Levobunolol | ratio Levobunolol | Ultracortenol | Vistagan | AKBeta | PMS-Levobunolol | PMS Levobunolol | PMSLevobunolol
Chemical Information
Molecular Formula C17H25NO3
CAS Registry Number 47141-42-4
SMILES CC(C)(C)NCC(COC1=CC=CC2=C1CCCC2=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Alopecia23.02.02.001--
Arrhythmia02.03.02.001--Not Available
Asthenia08.01.01.001--Not Available
Ataxia17.02.02.001; 08.01.02.004--
Atrioventricular block02.03.01.002--Not Available
Bradycardia02.03.02.002--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Cardiac arrest02.03.04.001--
Cardiac failure congestive02.05.01.002--Not Available
Cerebral ischaemia24.04.06.003; 17.08.01.005--
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chest pain08.01.08.002; 02.02.02.011; 22.02.08.003--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Conjunctivitis11.01.06.012; 06.04.01.002--
Depression19.15.01.001--
Diabetes mellitus14.06.01.001; 05.06.01.001--Not Available
Diarrhoea07.02.01.001--
Diplopia17.17.01.005; 06.02.06.002--Not Available
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.007--
Dyspnoea22.02.01.004; 02.01.03.002--
Erythema multiforme23.03.01.003; 10.01.03.015--
Eyelid ptosis17.17.02.004; 06.05.01.002--Not Available
Feeling abnormal08.01.09.014--Not Available
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Hypoaesthesia eye17.02.06.019; 06.01.01.007--Not Available
Hypoglycaemia14.06.03.001; 05.06.03.001--
Hypotension24.06.03.002--
Iridocyclitis06.04.03.001--Not Available
Keratitis06.04.02.002--
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