Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Levalbuterol tartrate
Drug ID BADD_D01264
Description Levosalbutamol, or levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). [Salbutamol] has been marketed as a racemic mixture, although beta2-agonist activity resides almost exclusively in the (R)-enantiomer. The enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has adverse effects have led to the development of an enantiomerically pure (R)-salbutamol formulation known as levosalbutamol (levalbuterol).
Indications and Usage Levosalbutamol's bronchodilator properties give it indications in treatment of COPD (chronic obstructive pulmonary disease, also known as chronic obstructive lung disease) and asthma.
Marketing Status Prescription
ATC Code Not Available
DrugBank ID DB13139
KEGG ID D04703
MeSH ID D064412
PubChem ID 10349032
TTD Drug ID D02ZJI
NDC Product Code 50384-4188; 63187-876; 69988-0045; 0591-2927; 63402-510; 63629-8822; 15308-0719
Synonyms Levalbuterol | Xopenex | Levalbuterol Hydrochloride | Hydrochloride, Levalbuterol | Levosalbutamol Hydrochloride | Hydrochloride, Levosalbutamol
Chemical Information
Molecular Formula C30H48N2O12
CAS Registry Number 34391-04-3
SMILES CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.C(C(C(=O)O)O)( C(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acne23.02.01.001--Not Available
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Angina pectoris24.04.04.002; 02.02.02.002--
Angioedema23.04.01.001; 10.01.05.009--Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Atrial fibrillation02.03.03.002--
Bronchitis11.01.09.001; 22.07.01.001--
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Conjunctivitis11.01.06.012; 06.04.01.002--
Constipation07.02.02.001--
Cough22.02.03.001--
Cyst16.02.02.002; 08.03.05.001--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry skin23.03.03.001--
Dysmenorrhoea21.01.01.002--
Dyspnoea02.01.03.002; 22.02.01.004--
Ear pain04.03.01.003--
Epistaxis22.04.03.001; 24.07.01.005--
Extrasystoles02.03.02.003--Not Available
Gastroenteritis11.01.07.004; 07.19.03.001--Not Available
Haematuria24.07.01.047; 20.02.01.006--
Headache17.14.01.001--
Herpes simplex23.09.03.001; 11.05.02.001--Not Available
Hypertension24.08.02.001--
Influenza22.07.02.001; 11.05.03.001--Not Available
Injury12.01.08.004--Not Available
Insomnia17.15.03.002; 19.02.01.002--
Lung disorder22.02.07.001--Not Available
Metabolic acidosis14.01.01.003--Not Available
Myalgia15.05.02.001--
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