Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Kanamycin sulfate
Drug ID BADD_D01227
Description Kanamycin (also known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections. Kanamycin is isolated from the bacterium Streptomyces kanamyceticus and its most commonly used form is kanamycin sulfate.
Indications and Usage For treatment of infections where one or more of the following are the known or suspected pathogens: E. coli, Proteus species (both indole-positive and indole-negative), E. aerogenes, K. pneumoniae, S. marcescens, and Acinetobacter species.
Marketing Status Prescription; Discontinued
ATC Code A07AA08; J01GB04; S01AA24
DrugBank ID DB01172
KEGG ID D00866
MeSH ID D007612
PubChem ID 441374
TTD Drug ID D0YV1Q
NDC Product Code 42513-0002; 51927-4938
Synonyms Kanamycin | Kantrex | Kanamycin A | Kanamycin Sulfate
Chemical Information
Molecular Formula C18H38N4O15S
CAS Registry Number 3847-27-6
SMILES C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N.OS(=O)(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Apnoea22.02.01.001--
Azotaemia20.01.01.001--Not Available
Carotene decreased13.02.05.005--Not Available
Deafness04.02.01.001--Not Available
Diarrhoea07.02.01.001--
Faecal fat increased13.05.02.002--Not Available
Headache17.14.01.001--
Malabsorption14.02.01.004; 07.17.01.001--
Meniere's disease17.02.12.003; 07.01.07.007; 04.04.02.003--Not Available
Nausea07.01.07.001--
Neurotoxicity17.02.10.002; 12.03.01.011--Not Available
Nystagmus17.02.02.006; 06.05.02.006--
Oliguria20.01.03.004--Not Available
Paraesthesia17.02.06.005--
Paralysis17.01.04.004--Not Available
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Tinnitus04.04.01.002; 17.04.07.004--
Vertigo17.02.12.002; 04.04.01.003--
Vestibular disorder17.02.02.008; 04.04.02.001--
Vomiting07.01.07.003--
Balance disorder17.02.02.007--Not Available
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