Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Kanamycin
Drug ID BADD_D01226
Description Kanamycin (also known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections. Kanamycin is isolated from the bacterium Streptomyces kanamyceticus and its most commonly used form is kanamycin sulfate.
Indications and Usage For treatment of infections where one or more of the following are the known or suspected pathogens: E. coli, Proteus species (both indole-positive and indole-negative), E. aerogenes, K. pneumoniae, S. marcescens, and Acinetobacter species.
Marketing Status Prescription; Discontinued
ATC Code A07AA08; J01GB04; S01AA24
DrugBank ID DB01172
KEGG ID C00304
MeSH ID D007612
PubChem ID 6032
TTD Drug ID D0YV1Q
NDC Product Code Not Available
Synonyms Kanamycin | Kantrex | Kanamycin A | Kanamycin Sulfate
Chemical Information
Molecular Formula C18H36N4O11
CAS Registry Number 59-01-8
SMILES C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Albuminuria20.02.01.001--Not Available
Apnoea22.02.01.001--
Application site irritation08.02.01.003; 12.07.01.003--Not Available
Application site pain12.07.01.004; 08.02.01.004--Not Available
Azotaemia20.01.01.001--Not Available
Body temperature increased13.15.01.001--Not Available
Deafness04.02.01.001--Not Available
Deafness neurosensory17.04.07.001; 04.02.01.002--Not Available
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Headache17.14.01.001--
Malabsorption14.02.01.004; 07.17.01.001--
Meniere's disease17.02.12.003; 07.01.07.007; 04.04.02.003--Not Available
Nausea07.01.07.001--
Nephropathy toxic20.05.03.002; 12.03.01.010--Not Available
Neurotoxicity17.02.10.002; 12.03.01.011--Not Available
Nystagmus17.02.02.006; 06.05.02.006--
Oliguria20.01.03.004--Not Available
Ototoxicity12.03.01.012; 04.03.01.004--Not Available
Pain08.01.08.004--
Paraesthesia17.02.06.005--
Paralysis17.01.04.004--Not Available
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Red blood cells urine positive13.13.02.003--Not Available
Tinnitus04.04.01.002; 17.04.07.004--
Urinary casts13.13.02.014--Not Available
Vertigo17.02.12.002; 04.04.01.003--
Vestibular disorder17.02.02.008; 04.04.02.001--
Vomiting07.01.07.003--
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