Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Isoniazid
Drug ID BADD_D01204
Description Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Indications and Usage For the treatment of all forms of tuberculosis in which organisms are susceptible.
Marketing Status approved; investigational
ATC Code J04AC01
DrugBank ID DB00951
KEGG ID D00346
MeSH ID D007538
PubChem ID 3767
TTD Drug ID D09XQF
NDC Product Code 60687-553; 0555-0071; 71610-395; 83112-071; 50090-0410; 63187-978; 0555-0066; 68788-9405; 71610-108; 12785-0003; 50090-0370; 70518-0096; 70518-2576; 43063-463; 62135-550; 0781-3056; 12785-0002; 66639-914; 51079-083; 43367-0100; 71052-611; 46287-009; 71335-0275; 53002-2920
UNII V83O1VOZ8L
Synonyms Isoniazid | Isonicotinic Acid Hydrazide | Hydrazide, Isonicotinic Acid | Phthivazide | Phthivazid | Isonicotinic Acid Vanillylidenehydrazide | Acid Vanillylidenehydrazide, Isonicotinic | Vanillylidenehydrazide, Isonicotinic Acid | Ftivazide | Tubazide | Isonex
Chemical Information
Molecular Formula C6H7N3O
CAS Registry Number 54-85-3
SMILES C1=CN=CC=C1C(=O)NN
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Kussmaul respiration22.02.01.008; 14.01.01.0040.002780%Not Available
Normal newborn18.08.06.0010.006115%Not Available
Renal glycosuria20.05.03.0200.002780%Not Available
Anti-neutrophil cytoplasmic antibody positive vasculitis24.12.04.002; 10.02.02.0230.002780%Not Available
Cell death14.11.02.005; 08.03.03.0030.002780%Not Available
Foaming at mouth17.02.05.056; 08.01.03.070; 07.05.05.0190.002780%Not Available
Primary progressive multiple sclerosis17.16.01.0050.002780%Not Available
Butterfly rash23.03.13.019; 15.06.02.010; 10.04.03.0100.002780%Not Available
Haemoperitoneum12.01.17.007; 07.07.02.007; 24.07.02.0650.002780%Not Available
Immune thrombocytopenia10.02.01.083; 01.08.01.0130.004170%Not Available
Vancomycin infusion reaction23.03.06.028; 10.01.01.0480.002780%Not Available
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ADReCS-Target
Drug Name ADR Term Target
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