Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Iohexol
Drug ID BADD_D01180
Description Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Indications and Usage Iohexol ia used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.
Marketing Status approved
ATC Code V08AB02
DrugBank ID DB01362
KEGG ID D01817
MeSH ID D007472
PubChem ID 3730
TTD Drug ID D02BLO
NDC Product Code 43228-100; 0407-1413; 71806-141; 0407-1414; 0407-1416; 0407-1415; 0407-1401; 0407-1411; 0407-1412; 65072-0801; 54702-501
UNII 4419T9MX03
Synonyms Iohexol | Iohexol 350 | Nycodenz | Compound 545 | Exypaque | Omnipaque
Chemical Information
Molecular Formula C19H26I3N3O9
CAS Registry Number 66108-95-0
SMILES CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Nasal congestion22.04.04.0010.372741%
Nasal obstruction22.12.03.0130.028454%Not Available
Nausea07.01.07.0011.187936%
Neck pain15.03.04.0090.024897%
Nephropathy20.05.03.0010.007113%Not Available
Nephropathy toxic20.05.03.002; 12.03.01.0100.128041%Not Available
Nervous system disorder17.02.10.001--Not Available
Neuralgia17.02.07.005--
Non-cardiogenic pulmonary oedema24.03.08.004; 22.01.03.006--Not Available
Ocular hyperaemia06.04.05.0040.167165%Not Available
Odynophagia07.01.06.0360.010670%Not Available
Oedema08.01.07.006; 14.05.06.0100.117371%Not Available
Oedema mouth23.04.01.008; 10.01.05.006; 07.05.04.001--Not Available
Oedema mucosal08.01.06.0120.007113%Not Available
Oliguria20.01.03.0040.010670%Not Available
Ophthalmoplegia17.17.02.005; 06.05.02.003--Not Available
Oral discomfort07.05.05.0010.019206%Not Available
Oral pain07.05.05.034--
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Pallor24.03.04.001; 23.03.03.031; 08.01.03.0320.115237%Not Available
Palpitations02.11.04.0120.146536%
Pancreatitis07.18.01.0010.046237%
Panic attack19.06.04.0010.014227%Not Available
Panic reaction19.06.04.0030.014227%Not Available
Papule23.03.03.0380.103144%Not Available
Paraesthesia23.03.03.094; 17.02.06.005--
Paralysis17.01.04.004--Not Available
Periorbital oedema06.08.03.017; 23.04.01.002; 10.01.05.0100.033433%
Peripheral coldness23.06.04.008; 24.04.03.006; 08.01.09.0100.021340%Not Available
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ADReCS-Target
Drug Name ADR Term Target
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