Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Iohexol
Drug ID BADD_D01180
Description Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Indications and Usage Iohexol ia used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.
Marketing Status Prescription; Discontinued
ATC Code V08AB02
DrugBank ID DB01362
KEGG ID D01817
MeSH ID D007472
PubChem ID 3730
TTD Drug ID D02BLO
NDC Product Code 0407-1411; 71806-141; 0407-1413; 0407-1412; 0407-1401; 0407-1415; 0407-1414; 0407-1416; 65072-0801
Synonyms Iohexol | Iohexol 350 | Nycodenz | Compound 545 | Exypaque | Omnipaque
Chemical Information
Molecular Formula C19H26I3N3O9
CAS Registry Number 66108-95-0
SMILES CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Nasal congestion22.04.04.001--
Nausea07.01.07.001--
Neck pain15.03.04.009--
Nervous system disorder17.02.10.001--Not Available
Neuralgia17.02.07.005--
Non-cardiogenic pulmonary oedema24.03.08.004; 22.01.03.006--Not Available
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Pancreatitis07.18.01.001--
Paraesthesia17.02.06.005--
Paralysis17.01.04.004--Not Available
Photophobia17.17.02.006; 06.01.01.004--
Presyncope17.02.05.009; 02.01.02.007; 24.06.02.010--
Pruritus23.03.12.001--
Pulmonary oedema22.01.03.003; 02.05.02.003--
Pyrexia08.05.02.003--
Quadriplegia17.01.04.013--Not Available
Radiculopathy17.10.01.005--
Rash23.03.13.001--Not Available
Renal failure20.01.03.005--Not Available
Restlessness19.11.02.002; 17.02.05.021--
Salivary gland enlargement07.06.03.002--Not Available
Seizure17.12.03.001--
Sensory disturbance17.02.07.006--Not Available
Shock24.06.02.002--Not Available
Skin disorder23.03.03.007--Not Available
Somnolence17.02.04.006; 19.02.05.003--
Speech disorder22.02.05.034; 19.19.02.002; 17.02.08.003--Not Available
Stupor19.02.05.004; 17.02.04.007--Not Available
Swelling08.01.03.015--Not Available
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