ADReCS

Pharmaceutical Information

Drug Name	Iohexol
Drug ID	BADD_D01180
Description	Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Indications and Usage	Iohexol ia used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.
Marketing Status	approved
ATC Code	V08AB02
DrugBank ID	DB01362
KEGG ID	D01817
MeSH ID	D007472
PubChem ID	3730
TTD Drug ID	D02BLO
NDC Product Code	43228-100; 0407-1413; 71806-141; 0407-1414; 0407-1416; 0407-1415; 0407-1401; 0407-1411; 0407-1412; 65072-0801; 54702-501
UNII	4419T9MX03
Synonyms	Iohexol \| Iohexol 350 \| Nycodenz \| Compound 545 \| Exypaque \| Omnipaque

Chemical Information

Molecular Formula	C19H26I3N3O9
CAS Registry Number	66108-95-0
SMILES	CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
Chemical Structure

ADRs Induced by Drug

*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..

ADR Term	ADReCS ID	ADR Frequency (FAERS)	ADR Severity Grade (FAERS)	ADR Severity Grade (CTCAE)
Erythema	23.03.06.001	1.646038%		Not Available
Erythema multiforme	23.03.01.003; 10.01.03.015	0.045526%
Erythema of eyelid	23.03.06.006; 06.04.04.003	0.029876%		Not Available
Extravasation	08.01.03.008	0.637360%		Not Available
Eye disorder	06.08.03.001	0.017783%		Not Available
Eye irritation	06.04.05.003	0.046237%		Not Available
Eye pain	06.08.03.002	0.017783%
Eye swelling	06.08.03.003	0.273154%		Not Available
Eyelid oedema	06.04.04.004; 23.04.01.003; 10.01.05.001	0.152226%		Not Available
Face oedema	23.04.01.004; 10.01.05.002; 08.01.07.003	0.079670%
Facial paralysis	17.04.03.008	0.007113%		Not Available
Feeling abnormal	08.01.09.014	0.133732%		Not Available
Feeling cold	08.01.09.008	0.069000%		Not Available
Feeling hot	08.01.09.009	0.181391%		Not Available
Flatulence	07.01.04.002	-	-
Flushing	23.06.05.003; 08.01.03.025; 24.03.01.002	0.314412%
Food allergy	10.01.01.012	0.007113%		Not Available
Gastrointestinal disorder	07.11.01.001	-	-	Not Available
Gastrointestinal pain	07.01.05.005	-	-
Generalised oedema	14.05.06.007; 08.01.07.004	0.007113%
Gingival swelling	07.09.13.013	-	-	Not Available
Glossitis	07.14.01.001	0.007113%		Not Available
Glossodynia	07.14.02.001	-	-	Not Available
Guillain-Barre syndrome	11.07.01.001; 10.04.10.005; 17.09.01.001	-	-
Haematemesis	24.07.02.011; 07.12.02.002	0.017783%		Not Available
Haematoma	24.07.01.001	-	-
Haemoptysis	02.11.04.009; 24.07.01.006; 22.02.03.004	0.024897%		Not Available
Hallucination	19.10.04.003	-	-
Headache	17.14.01.001	-	-
Hemiplegia	17.01.04.002	0.010670%		Not Available

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