Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Interferon beta-1a
Drug ID BADD_D01169
Description Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
Indications and Usage For treatment of relapsing/remitting multiple sclerosis, also for condyloma acuminatum
Marketing Status Prescription
ATC Code L03AB07
DrugBank ID DB00060
KEGG ID D04554
MeSH ID D000068556
PubChem ID Not Available
TTD Drug ID D0V4JQ
NDC Product Code 59627-333; 59627-111; 44087-0044; 44087-3344; 59627-003; 59627-002; 44087-8822; 44087-0188; 44087-3322; 59627-222; 59627-125; 44087-0022
Synonyms Interferon beta-1a | beta-1a, Interferon | Interferon beta 1a | beta 1a, Interferon | Avonex Pen | Rebif | Avonex
Chemical Information
Molecular Formula Not Available
CAS Registry Number 145258-61-3
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Injection site reaction12.07.03.015; 08.02.03.014--
Menorrhagia21.01.03.002--
Metrorrhagia21.01.01.006--Not Available
Migraine24.03.05.003; 17.14.02.001--Not Available
Muscular weakness17.05.03.005; 15.05.06.001--
Myalgia15.05.02.001--
Nausea07.01.07.001--
Pain08.01.08.004--
Pancytopenia01.03.03.003--Not Available
Paraesthesia17.02.06.005--
Peripheral ischaemia24.04.03.002--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Seizure17.12.03.001--
Sinusitis22.07.03.007; 11.01.13.005--
Suicidal ideation19.12.01.003--
Thrombocytopenia01.08.01.002--Not Available
Toothache07.09.06.001--
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urinary tract infection20.08.02.001; 11.01.14.004--
Vomiting07.01.07.003--
Injection site cellulitis11.02.01.012; 08.02.03.037; 23.09.01.009; 12.07.03.037--Not Available
Vasodilation procedure25.03.01.001--Not Available
Hepatic enzyme increased13.03.01.019--Not Available
Mental disorder19.07.01.002--Not Available
Urine analysis abnormal13.13.02.008--Not Available
Immune thrombocytopenic purpura10.04.01.008; 01.08.01.007--Not Available
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