Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Interferon beta-1a
Drug ID BADD_D01169
Description Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
Indications and Usage For treatment of relapsing/remitting multiple sclerosis, also for condyloma acuminatum
Marketing Status Prescription
ATC Code L03AB07
DrugBank ID DB00060
KEGG ID D04554
MeSH ID D000068556
PubChem ID Not Available
TTD Drug ID D0V4JQ
NDC Product Code 59627-333; 59627-111; 44087-0044; 44087-3344; 59627-003; 59627-002; 44087-8822; 44087-0188; 44087-3322; 59627-222; 59627-125; 44087-0022
Synonyms Interferon beta-1a | beta-1a, Interferon | Interferon beta 1a | beta 1a, Interferon | Avonex Pen | Rebif | Avonex
Chemical Information
Molecular Formula Not Available
CAS Registry Number 145258-61-3
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Alopecia23.02.02.001--
Anaemia01.03.02.001--
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Arthralgia15.01.02.001--
Asthenia08.01.01.001--Not Available
Bronchitis22.07.01.001; 11.01.09.001--
Cardiac failure congestive02.05.01.002--Not Available
Cardiomyopathy02.04.01.001--Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Chills15.05.03.016; 08.01.09.001--
Depression19.15.01.001--
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.007--
Eye disorder06.08.03.001--Not Available
Fatigue08.01.01.002--
Headache17.14.01.001--
Hepatic failure09.01.03.002--
Hepatitis09.01.07.004--Not Available
Hyperthyroidism14.11.01.011; 05.02.02.001--
Hypertonia17.05.02.001; 15.05.04.007--Not Available
Hypothyroidism14.11.01.012; 05.02.03.001--
Infection11.01.08.002--Not Available
Influenza like illness08.01.03.010--
Injection site abscess12.07.03.021; 11.01.08.023; 08.02.03.021--Not Available
Injection site atrophy12.07.03.022; 08.02.03.022--Not Available
Injection site haemorrhage24.07.01.010; 12.07.03.005; 08.02.03.005--Not Available
Injection site inflammation12.07.03.009; 08.02.03.008--Not Available
Injection site necrosis08.02.03.020; 12.07.03.020--Not Available
Injection site oedema12.07.03.024; 08.02.03.024--Not Available
Injection site pain12.07.03.011; 08.02.03.010--Not Available
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