| Drug Name |
Insulin glargine |
| Drug ID |
BADD_D01163 |
| Description |
Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas that promotes glucose metabolism. Insulin is released from the pancreas following a meal to promote the uptake of glucose from the blood into internal organs and tissues such as the liver, fat cells, and skeletal muscle. Absorption of glucose into cells allows for its transformation into glycogen or fat for storage. Insulin also inhibits hepatic glucose production, enhances protein synthesis, and inhibits lipolysis and proteolysis. |
| Indications and Usage |
For the treatment of Type 1 or 2 diabetes mellitus in patients over 17 years old who require a long-acting (basal) insulin for the control of hyperglycemia. May be used in pediatric patients with Type 1 diabetes mellitus who require a long-acting (basal) insulin for glycemic control. |
| Marketing Status |
Prescription |
| ATC Code |
A10AE04 |
| DrugBank ID |
DB00047
|
| KEGG ID |
D03250
|
| MeSH ID |
D000069036
|
| PubChem ID |
118984454
|
| TTD Drug ID |
Not Available
|
| NDC Product Code |
50090-2193; 49502-196; 49502-195; 70518-1390; 0002-9524; 0002-1437; 50090-4177; 0002-8214; 0088-2220; 50090-1398; 0088-5020; 52221-125; 50090-5835; 50090-4068; 0002-1076; 50090-0876; 62381-7661; 0088-5021; 0088-2219; 0024-5869; 0002-7715; 0024-5871 |
| Synonyms |
Insulin Glargine | Glargine, Insulin | A21-Gly-B31-Arg-B32-Arg-insulin | A21 Gly B31 Arg B32 Arg insulin | Insulin, Glycyl(A21)-Arginyl(B31,B32) | Glargine | Insulin, Gly(A21)-Arg(B31,B32) | Lantus | Lantus Solostar | Solostar, Lantus | Basaglar | HOE 901 | 901, HOE | HOE-901 | HOE901 |
