Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Indinavir
Drug ID BADD_D01150
Description A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]
Indications and Usage Indinavir is an antiretroviral drug for the treatment of HIV infection.
Marketing Status approved
ATC Code J05AE02
DrugBank ID DB00224
KEGG ID D03833
MeSH ID D019469
PubChem ID 5362440
TTD Drug ID D0V7CF
NDC Product Code Not Available
UNII 5W6YA9PKKH
Synonyms Indinavir | MK-639 | MK 639 | MK639 | L-735 524 | L 735 524 | L735 524 | L-735,524 | L 735,524 | L735,524 | Crixivan | Indinavir Sulfate | Sulfate, Indinavir | Indinavir, Sulfate (1:1)
Chemical Information
Molecular Formula C36H47N5O4
CAS Registry Number 150378-17-9
SMILES CC(C)(C)NC(=O)C1CN(CCN1CC(CC(CC2=CC=CC=C2)C(=O)NC3C(CC4=CC=CC=C34)O)O)CC5=CN=CC= C5
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypersensitivity vasculitis10.02.02.017; 24.12.04.013; 23.06.02.005; 01.01.04.008--Not Available
Hypertriglyceridaemia14.08.02.001--
Hypoaesthesia23.03.03.081; 17.02.06.023--Not Available
Immune system disorder10.02.01.001--Not Available
Increased appetite08.01.09.027; 14.03.01.003--Not Available
Influenza like illness08.01.03.010--
Ingrowing nail23.02.05.011--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Insulin resistance05.06.02.003; 14.06.02.003--Not Available
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Lipoatrophy23.07.01.001; 14.08.04.006--
Loss of consciousness17.02.04.004--Not Available
Lymphadenopathy01.09.01.002--Not Available
Malaise08.01.01.003--
Muscle contractions involuntary15.05.03.008; 17.05.03.001--Not Available
Muscle spasms15.05.03.004--
Muscular weakness17.05.03.005; 15.05.06.001--
Musculoskeletal pain15.03.04.007--
Myalgia15.05.02.001--
Myocardial infarction24.04.04.009; 02.02.02.007--
Myositis15.05.01.001--
Nausea07.01.07.001--
Nephritis20.05.02.001--Not Available
Nephrolithiasis20.04.01.002--
Nervous system disorder17.02.10.001--Not Available
Nervousness19.06.02.003--Not Available
Neuralgia17.02.07.005--
Neuropathy peripheral17.09.03.003--Not Available
Neurosis19.06.01.001--Not Available
Neutrophil count increased13.01.06.011--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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