Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Iloprost
Drug ID BADD_D01135
Description Iloprost is a synthetic analogue of prostacyclin PGI2 that dilates systemic and pulmonary arterial vascular beds. It is used to treat pulmonary arterial hypertension (PAH).
Indications and Usage Used for the treatment of pulmonary arterial hypertension.
Marketing Status approved; investigational
ATC Code B01AC11
DrugBank ID DB01088
KEGG ID D02721
MeSH ID D016285
PubChem ID 5311181
TTD Drug ID D05ZTH
NDC Product Code 66215-303; 40016-013; 82231-109; 54893-0017; 66215-302
UNII JED5K35YGL
Synonyms Iloprost | Ciloprost | ZK-36374 | ZK 36374 | ZK36374 | Ventavis
Chemical Information
Molecular Formula C22H32O4
CAS Registry Number 78919-13-8
SMILES CC#CCC(C)C(C=CC1C(CC2C1CC(=CCCCC(=O)O)C2)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Secretion discharge08.01.03.0190.000082%Not Available
Haemorrhage24.07.01.002--Not Available
Lung neoplasm malignant22.08.01.001; 16.19.02.0010.000206%Not Available
Vasodilation procedure25.03.01.001--Not Available
Intestinal haemorrhage24.07.02.031; 07.12.03.0050.000206%Not Available
Angiopathy24.03.02.007--Not Available
Blood alkaline phosphatase increased13.04.02.004--
Cardiac disorder02.11.01.0030.000535%Not Available
Connective tissue disorder10.04.04.026; 15.06.01.006--Not Available
Embolism24.01.01.0090.000082%
Infarction24.04.02.0170.000123%Not Available
Inflammation10.02.01.089; 08.01.05.0070.000247%Not Available
Malnutrition14.03.02.0040.000082%Not Available
Mediastinal disorder22.09.03.001--Not Available
Sudden hearing loss04.02.01.0090.000082%Not Available
Blood disorder01.05.01.004--Not Available
Immunodeficiency10.03.02.0020.000082%Not Available
Disease progression08.01.03.0380.001522%
Obstructive airways disorder22.03.01.0110.000082%Not Available
Poor quality sleep17.15.04.002; 19.02.05.0050.000164%Not Available
Pulmonary arterial hypertension24.08.03.003; 22.06.01.0020.003537%Not Available
Low birth weight baby18.04.02.0030.000288%Not Available
Brain injury19.07.03.007; 17.11.01.0030.000206%Not Available
Oropharyngeal discomfort22.12.03.015; 07.05.05.0080.000164%Not Available
Oropharyngeal pain22.12.03.016; 07.05.05.0040.000387%
Hepatic cancer16.07.02.004; 09.04.02.0080.000123%Not Available
Multiple organ dysfunction syndrome08.01.03.0570.000288%
Concomitant disease aggravated08.01.03.0630.000206%Not Available
Terminal state08.01.03.0790.000164%Not Available
Disease complication08.01.03.0870.000288%Not Available
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