Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Idarubicin
Drug ID BADD_D01127
Description An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Indications and Usage For the treatment of acute myeloid leukemia (AML) in adults. This includes French-American-British (FAB) classifications M1 through M7.
Marketing Status approved
ATC Code L01DB06
DrugBank ID DB01177
KEGG ID D08062
MeSH ID D015255
PubChem ID 42890
TTD Drug ID D01XDL
NDC Product Code Not Available
UNII ZRP63D75JW
Synonyms Idarubicin | 4-Desmethoxydaunorubicin | 4 Desmethoxydaunorubicin | 4-Demethoxydaunorubicin | 4 Demethoxydaunorubicin | IMI-30 | IMI 30 | IMI30 | NSC-256439 | NSC 256439 | NSC256439 | Idarubicin Hydrochloride | Hydrochloride, Idarubicin
Chemical Information
Molecular Formula C26H27NO9
CAS Registry Number 58957-92-9
SMILES CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Shock24.06.02.002--Not Available
Sinus tachycardia02.03.03.010--
Skin disorder23.03.03.007--Not Available
Skin hyperpigmentation23.05.01.003--
Stomatitis07.05.06.005--
Thrombocytopenia01.08.01.002--Not Available
Thrombophlebitis24.01.02.001--Not Available
Ulcer08.03.06.001--Not Available
Urethral disorder20.07.01.002--Not Available
Urinary tract disorder20.08.01.001--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vomiting07.01.07.003--
Cardiotoxicity02.11.01.009; 12.03.01.007--Not Available
Tachyarrhythmia02.03.02.008--Not Available
Acute coronary syndrome24.04.04.011; 02.02.02.015--Not Available
Lymphatic disorder01.09.01.003--Not Available
Haemorrhage24.07.01.002--Not Available
Gastrointestinal toxicity07.08.03.006; 12.03.01.019--Not Available
Angiopathy24.03.02.007--Not Available
Hot flush24.03.01.005; 21.02.02.001; 08.01.03.027--
Recall phenomenon23.03.07.005; 12.02.06.001--
Embolism24.01.01.009--
Malnutrition14.03.02.004--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Blood disorder01.05.01.004--Not Available
Neutropenic colitis07.08.01.014; 01.02.03.010--Not Available
Bone marrow failure01.03.03.005--
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ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene