Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ibandronic acid
Drug ID BADD_D01117
Description Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to [zoledronic acid], [minodronic acid], and [risedronic acid].[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs.[A203138] Ibandronate was granted FDA approval on 16 May 2003.[L13805]
Indications and Usage For the treatment and prevention of osteoporosis in postmenopausal women.[L13805,L13808]
Marketing Status approved; investigational
ATC Code M05BA06
DrugBank ID DB00710
KEGG ID D08056
MeSH ID D000077557
PubChem ID 60852
TTD Drug ID D08SJZ
NDC Product Code Not Available
UNII UMD7G2653W
Synonyms Ibandronic Acid | Ibandronate | 1-Hydroxy-3-(methylpentylamino)propylidenebisphosphonate | (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonate | Ibandronate Sodium Anhydrous | Boniva | Bonviva | Ibandronate Sodium | Ibandronic Acid, Sodium Salt, Monohydrate | RPR 102289A | RPR-102289A | RPR102289A | Bondronat | BM 21.0955 | BM 210955 | BM-21.0955 | BM21.0955 | BM-210955 | BM210955
Chemical Information
Molecular Formula C9H23NO7P2
CAS Registry Number 114084-78-5
SMILES CCCCCN(C)CCC(O)(P(=O)(O)O)P(=O)(O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Rash23.03.13.001--Not Available
Rash erythematous23.03.13.029--Not Available
Rash macular23.03.13.003--Not Available
Rash papular23.03.13.017--Not Available
Renal cyst20.01.04.001; 16.27.01.001--Not Available
Renal failure20.01.03.005--Not Available
Rheumatoid arthritis15.01.03.001; 10.04.06.0010.001394%Not Available
Scleritis10.02.01.025; 06.04.07.002--Not Available
Shock24.06.02.002--Not Available
Skin discolouration23.03.03.0050.001077%Not Available
Skin disorder23.03.03.007--Not Available
Skin lesion23.03.03.0100.001077%Not Available
Sleep disorder19.02.04.001--Not Available
Stomatitis07.05.06.005--
Stridor22.04.02.003--
Swelling08.01.03.0150.009313%Not Available
Swollen tongue10.01.05.015; 23.04.01.014; 07.14.02.0030.000697%Not Available
Temporomandibular joint syndrome17.14.01.017; 15.01.08.0080.003389%Not Available
Tenderness08.01.08.0050.001077%Not Available
Thirst14.03.02.007; 08.01.09.021--Not Available
Thrombophlebitis24.01.02.0010.001394%Not Available
Tongue geographic07.14.01.0060.000697%Not Available
Tooth disorder07.09.05.0010.005322%Not Available
Tooth loss12.01.17.026; 07.09.09.0010.002091%Not Available
Toothache07.09.06.0010.004086%
Ulcer08.03.06.001--Not Available
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urethral disorder20.07.01.002--Not Available
Urinary retention20.02.02.011--
Urinary tract disorder20.08.01.001--Not Available
The 7th Page    First    Pre   7 8 9 10    Next   Last    Total 10 Pages