| Drug Name |
Hydroxyzine |
| Drug ID |
BADD_D01111 |
| Description |
Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties.[A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.[L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in allergic medications, and is responsible for much of its hydroxyzine's antihistaminic effect.[A189753] Hydroxyzine is also used for generalized anxiety disorder, tension caused by psychoneurosis, and other conditions with manifestations of anxiety.[L9677] |
| Indications and Usage |
For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
N05BB01 |
| DrugBank ID |
DB00557
|
| KEGG ID |
D08054
|
| MeSH ID |
D006919
|
| PubChem ID |
3658
|
| TTD Drug ID |
D0O6SX
|
| NDC Product Code |
65162-575; 65162-577; 63187-492; 52584-601; 52584-610; 65162-671; 0404-9878; 52584-007 |
| Synonyms |
Hydroxyzine | 2-(2-(4-((4-Chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)ethanol | Hydroxyzine Dihydrochloride | Vistaril | Hydroxyzine Pamoate | Pamoate, Hydroxyzine | Orgatrax | Durrax | Atarax | Hydroxyzine Hydrochloride |
