Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Hydroxypropyl cellulose
Drug ID BADD_D01109
Description Hydroxypropyl cellulose is an ether of cellulose where some of the hydroxyl groups of the cellulose have been hydroxypropylated forming -OCH2CH(OH)CH3 groups. Lacrisertis a formulation of hydroxypropyl cellulose that is used for artificial tears. It is used to treat syndromes characterized by insufficient tear production (keratoconjunctivitis sicca), recurrent corneal erosions, decreased corneal sensitivity, exposure and neuroparalytic keratitis, and as a lubricant for artificial eyes. As a food additive, hydroxypropyl cellulose is used as a thickener and as an emulsion stabilizer.
Indications and Usage Used to relieve dryness and irritation caused by reduced tear flow that occurs in certain eye diseases (keratoconjunctivitis sicca), recurrent corneal erosions, decreased corneal sensitivity, exposure and neuroparalytic keratitis, and as a lubricant for artificial eyes.
Marketing Status Prescription
ATC Code Not Available
DrugBank ID DB00840
KEGG ID D04478
MeSH ID C008079
PubChem ID Not Available
TTD Drug ID D0E6CH
NDC Product Code 24208-800; 55718-130
Synonyms hydroxypropylcellulose | hyprolose | hydroxypropyl cellulose, unspecified | hydroxypropyl cellulose | cellulose hydroxypropyl ether | hydroxypropyl cellulose (type H) | hydroxypropyl cellulose (1600000 WAMW) | hydroxypropyl cellulose (1200000 MW) | Zilactin | Zilactin B | Lacrisert | low-substituted hydroxypropylcellulose
Chemical Information
Molecular Formula Not Available
CAS Registry Number 9004-64-2
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Eye irritation06.04.05.003--Not Available
Eyelid oedema06.04.04.004; 23.04.01.003; 10.01.05.001--Not Available
Hyperaemia24.03.02.002--Not Available
Hypersensitivity10.01.03.003--
Photophobia17.17.02.006; 06.01.01.004--
Vision blurred17.17.01.010; 06.02.06.007--
Growth of eyelashes06.06.04.007--Not Available
Ocular discomfort06.08.03.008--Not Available
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