Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Hexachlorophene
Drug ID BADD_D01068
Description A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
Indications and Usage For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Marketing Status Prescription; Discontinued
ATC Code D08AE01
DrugBank ID DB00756
KEGG ID D00859
MeSH ID D006582
PubChem ID 3598
TTD Drug ID D0ZX2G
NDC Product Code Not Available
Synonyms Hexachlorophene | Hexachlorophane
Chemical Information
Molecular Formula C13H6Cl6O2
CAS Registry Number 70-30-4
SMILES C1=C(C(=C(C(=C1Cl)Cl)CC2=C(C(=CC(=C2Cl)Cl)Cl)O)O)Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dermatitis23.03.04.002--Not Available
Dry skin23.03.03.001--
Erythema23.03.06.001--Not Available
Hypersensitivity10.01.03.003--
Photosensitivity reaction23.03.09.003--
Skin exfoliation23.03.07.003--Not Available
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