| Pharmaceutical Information |
| Drug Name |
Guanethidine monosulfate |
| Drug ID |
BADD_D01045 |
| Description |
An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues. [PubChem] |
| Indications and Usage |
For the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension. |
| Marketing Status |
Discontinued |
| ATC Code |
C02CC02; S01EX01 |
| DrugBank ID |
DB01170
|
| KEGG ID |
D04382
|
| MeSH ID |
D006145
|
| PubChem ID |
56927696
|
| TTD Drug ID |
D0N3PE
|
| NDC Product Code |
Not Available |
| Synonyms |
Guanethidine | Oktadin | ((2-Hexahydro-1(2H)-azocinyl)ethyl)guanidine | Octadine | Guanethidine Sulfate | Sulfate, Guanethidine | Guanethidine Sulfate (2:1) | Guanethidine Sulfate (1:2) | Ismelin | Isobarin | Guanethidine Monosulfate | Monosulfate, Guanethidine | Guanethidine Sulfate (1:1) | Guanethidine Sulfate (2:1), 14C-Labeled |
|
| Chemical Information |
| Molecular Formula |
C10H24N4O4S |
| CAS Registry Number |
60-02-6 |
| SMILES |
[H+].[H+].C1CCCN(CCC1)CCN=C(N)N.[O-]S(=O)(=O)[O-] |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
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|
