Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Glatiramer acetate
Drug ID BADD_D01021
Description Glatiramer acetate consists of the acetate salts of synthetic polypeptides, containing four naturally occurring amino acids: L-glutamic acid, L-alanine, L-tyrosine, and L-lysine with an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. The average molecular weight of glatiramer acetate is 5,000-9,000 daltons. It is an immunomodulator, licensed in much of the world for reduced frequency of relapses in relapsing-remitting multiple sclerosis.
Indications and Usage For reduction of the frequency of relapses in patients with Relapsing-Remitting Multiple Sclerosis.
Marketing Status Prescription; Discontinued
ATC Code L03AX13
DrugBank ID DB05259
KEGG ID D04318
MeSH ID D000068717
PubChem ID 3081884
TTD Drug ID D04CRL
NDC Product Code 0441-3642; 0378-6960; 63629-8815; 68546-317; 63629-8816; 65129-1181; 63850-4035; 55111-945; 24795-0063; 0781-3250; 59651-517; 53104-7715; 14403-0008; 0781-3234; 24795-0068; 68546-325
Synonyms Glatiramer Acetate | Acetate, Glatiramer | Copaxone | Glatiramer | TV 5010 | 5010, TV | TV5010 | TV-5010
Chemical Information
Molecular Formula C25H45N5O13
CAS Registry Number 147245-92-9
SMILES CC(C(=O)O)N.CC(=O)O.C1=CC(=CC=C1CC(C(=O)O)N)O.C(CCN)CC(C(=O)O)N.C(CC(=O)O)C(C(=O )O)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Coma17.02.09.001--Not Available
Confusional state17.02.03.005; 19.13.01.001--
Conjunctivitis06.04.01.002; 11.01.06.012--
Constipation07.02.02.001--
Coordination abnormal17.02.02.004--Not Available
Coronary artery occlusion24.04.04.013; 02.02.01.006--Not Available
Cough22.02.03.001--
Cushing's syndrome14.11.01.007; 05.01.01.001; 24.08.04.001; 19.07.03.002--Not Available
Cushingoid24.08.02.004; 19.07.03.001; 14.11.01.006; 05.01.01.002--
Cyanosis22.02.02.007; 02.01.02.002; 24.03.01.007--
Cyst16.02.02.002; 08.03.05.001--Not Available
Cystitis20.03.02.002; 11.01.14.001--
Deafness04.02.01.001--Not Available
Dental caries07.09.01.001--
Depressed level of consciousness17.02.04.002--
Dermatitis23.03.04.002--Not Available
Dermatitis bullous23.03.01.002--
Dermatitis contact12.03.01.040; 23.03.04.004; 10.01.01.003--Not Available
Diarrhoea07.02.01.001--
Diplegia17.01.04.015--Not Available
Diplopia17.17.01.005; 06.02.06.002--Not Available
Discomfort08.01.08.003--Not Available
Disturbance in attention19.21.02.002; 17.03.03.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry eye06.08.02.001--
Dry mouth07.06.01.002--
Dry skin23.03.03.001--
Duodenal ulcer07.04.02.002--
Dysaesthesia17.02.06.003--
Dysgeusia17.02.07.003; 07.14.03.001--
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