Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ganciclovir
Drug ID BADD_D01003
Description An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Indications and Usage For induction and maintenance in the treatment of cytomegalovirus (CMV) retinitis in immunocompromised patients, including patients with acquired immunodeficiency syndrome (AIDS). Also used in the treatment of severe cytomegalovirus (CMV) disease, including CMV pneumonia, CMV gastrointestinal disease, and disseminated CMV infections, in immunocompromised patients.
Marketing Status approved; investigational
ATC Code J05AB06; S01AD09
DrugBank ID DB01004
KEGG ID D00333
MeSH ID D015774
PubChem ID 135398740
TTD Drug ID D05ARP
NDC Product Code 12806-6941; 51754-2500; 12869-803; 59651-108; 24208-535; 42023-173
UNII P9G3CKZ4P5
Synonyms Ganciclovir | Gancyclovir | BW-759 | Ganciclovir Sodium | Ganciclovir, Monosodium Salt | RS-21592 | BIOLF-62 | Cytovene
Chemical Information
Molecular Formula C9H13N5O4
CAS Registry Number 82410-32-0
SMILES C1=NC2=C(N1COC(CO)CO)N=C(NC2=O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blood culture positive13.08.02.002--Not Available
Blood glucose decreased13.02.02.001--Not Available
Blood lactate dehydrogenase increased13.04.02.002--
Blood magnesium decreased13.11.01.008--Not Available
Blood urea increased13.13.01.006--Not Available
Blood urine13.13.02.011--Not Available
Body temperature increased13.15.01.001--Not Available
Bone pain15.02.01.001--
Breast pain21.05.05.003--
Bronchospasm22.03.01.004; 10.01.03.012--
Cachexia16.32.03.011; 14.03.02.001; 08.01.01.009--Not Available
Cardiac arrest02.03.04.001--
Cataract06.06.01.001--
Cellulitis11.02.01.001; 23.11.02.004--Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Chills15.05.03.016; 08.01.09.001--
Cholelithiasis09.03.01.002--Not Available
Cholestasis09.01.01.001--Not Available
Coma17.02.09.001--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Congenital anomaly03.02.01.001--Not Available
Conjunctivitis06.04.01.002; 11.01.06.012--
Constipation07.02.02.001--
Cough22.02.03.001--
Creatinine renal clearance decreased13.13.01.013--Not Available
Deafness04.02.01.001--Not Available
Dehydration14.05.05.001--
Dermatitis23.03.04.002--Not Available
Dermatitis bullous23.03.01.002--
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ADReCS-Target
Drug Name ADR Term Target
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