Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Gadodiamide hydrate
Drug ID BADD_D00986
Description Gadodiamide is a paramagnetic gadolinium-based contrast agent (GBCA) that is used in MR imaging procedures to assist in the visualization of blood vessels. It is intravenously injected and is commonly marketed under the trade name Omniscan.
Indications and Usage For intravenous use in MRI to visualize lesions with abnormal vascularity (or those thought to cause abnormalities in the blood-brain barrier) in the brain (intracranial lesions), spine, and associated tissues.
Marketing Status Prescription; Discontinued
ATC Code V08CA03
DrugBank ID DB00225
KEGG ID D01645
MeSH ID C064925
PubChem ID 153921
TTD Drug ID D03EEH
NDC Product Code 0407-0690; 0407-0691; 71806-069
Synonyms gadodiamide | Gd-DTPA bis-(methylamide) | Gd-DTPA-BMA | Omniscan | Omniscan Unique Softpack
Chemical Information
Molecular Formula C16H26GdN5O8
CAS Registry Number 131410-48-5
SMILES CNC(=O)CN(CCN(CCN(CC(=O)NC)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Gd+3]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Feeling abnormal08.01.09.014--Not Available
Feeling hot08.01.09.009--Not Available
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Gastrointestinal pain07.01.05.005--
Hallucination19.10.02.002--
Headache17.14.01.001--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypotension24.06.03.002--
Injection site pain12.07.03.011; 08.02.03.010--Not Available
Injection site reaction12.07.03.015; 08.02.03.014--
Instillation site pain12.07.01.008; 08.02.01.008--Not Available
Loss of consciousness17.02.04.004--Not Available
Malaise08.01.01.003--
Melaena24.07.02.013; 07.12.02.004--Not Available
Menopausal symptoms21.02.02.002--Not Available
Migraine24.03.05.003; 17.14.02.001--Not Available
Multiple sclerosis10.04.10.008; 17.16.01.001--Not Available
Myalgia15.05.02.001--
Myocardial infarction24.04.04.009; 02.02.02.007--
Myocardial ischaemia24.04.04.010; 02.02.02.008--Not Available
Nausea07.01.07.001--
Nervous system disorder17.02.10.001--Not Available
Neuropathy peripheral17.09.03.003--Not Available
Pain08.01.08.004--
Paraesthesia17.02.06.005--
Paresis17.01.04.008--Not Available
Personality disorder19.05.02.002--Not Available
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Pruritus23.03.12.001--
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