Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Frovatriptan
Drug ID BADD_D00976
Description Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.
Indications and Usage For the acute treatment of migraine attacks with or without aura in adults.
Marketing Status Prescription
ATC Code N02CC07
DrugBank ID DB00998
KEGG ID D07997
MeSH ID C108128
PubChem ID 77992
TTD Drug ID D06FPQ
NDC Product Code 0378-3140
Synonyms frovatriptan | 3-methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole | Frova | VML-251 | VML251 | Frovelan | SB 209509 | Allegro | frovatriptan succinate | (+)-(R)-5,6,7,8-tetrahydro-6-(methylamino)carbazole-3-carboxamide succinate (1:1), monohydrate
Chemical Information
Molecular Formula C14H17N3O
CAS Registry Number 158747-02-5
SMILES CNC1CCC2=C(C1)C3=C(N2)C=CC(=C3)C(=O)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Oesophageal spasm07.02.04.004--Not Available
Osteoarthritis15.01.04.001--Not Available
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Pain in jaw15.02.01.003--Not Available
Palpitations02.01.02.003--
Paraesthesia17.02.06.005--
Peptic ulcer07.04.07.001--Not Available
Personality disorder19.05.02.002--Not Available
Pharyngitis07.05.07.004; 22.07.03.004; 11.01.13.003--
Pollakiuria20.02.02.007--
Polyuria20.02.03.002--Not Available
Prinzmetal angina24.04.04.015; 02.02.02.019--Not Available
Pruritus23.03.12.001--
Purpura01.01.04.003; 23.06.01.004; 24.07.06.005--
Reflexes abnormal17.02.01.006--Not Available
Renal pain20.02.03.003--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Salivary gland pain07.06.02.002--Not Available
Salivary hypersecretion07.06.01.009--Not Available
Seizure17.12.03.001--
Sensory loss17.02.07.007--Not Available
Serotonin syndrome17.05.02.004; 15.05.04.016; 12.03.01.041--Not Available
Shock24.06.02.002--Not Available
Sinusitis22.07.03.007; 11.01.13.005--
Somnolence17.02.04.006; 19.02.05.003--
Speech disorder22.02.05.034; 19.19.02.002; 17.02.08.003--Not Available
Stomatitis07.05.06.005--
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Tachycardia02.03.02.007--Not Available
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