Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Frovatriptan
Drug ID BADD_D00976
Description Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.
Indications and Usage For the acute treatment of migraine attacks with or without aura in adults.
Marketing Status Prescription
ATC Code N02CC07
DrugBank ID DB00998
KEGG ID D07997
MeSH ID C108128
PubChem ID 77992
TTD Drug ID D06FPQ
NDC Product Code 0378-3140
Synonyms frovatriptan | 3-methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole | Frova | VML-251 | VML251 | Frovelan | SB 209509 | Allegro | frovatriptan succinate | (+)-(R)-5,6,7,8-tetrahydro-6-(methylamino)carbazole-3-carboxamide succinate (1:1), monohydrate
Chemical Information
Molecular Formula C14H17N3O
CAS Registry Number 158747-02-5
SMILES CNC1CCC2=C(C1)C3=C(N2)C=CC(=C3)C(=O)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Disturbance in attention19.21.02.002; 17.03.03.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Dysaesthesia17.02.06.003--
Dysgeusia07.14.03.001; 17.02.07.003--
Dyspepsia07.01.02.001--
Dysphagia07.01.06.003--
Dyspnoea22.02.01.004; 02.01.03.002--
Ear pain04.03.01.003--
Electrocardiogram abnormal13.14.05.001--Not Available
Epistaxis24.07.01.005; 22.04.03.001--
Eructation07.01.02.003--
Euphoric mood19.04.02.006--
Eye pain06.08.03.002--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Feeling cold08.01.09.008--Not Available
Feeling hot08.01.09.009--Not Available
Feeling of relaxation08.01.09.017--Not Available
Flatulence07.01.04.002--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Gait disturbance17.02.05.016; 08.01.02.002--
Gastrooesophageal reflux disease07.02.02.003--
Gastrointestinal pain07.01.05.005--
Haemoglobin13.01.05.018--Not Available
Headache17.14.01.001--
Hiccups22.02.04.002; 07.01.06.009--
Hyperacusis17.04.03.003; 04.02.02.001--Not Available
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