| Drug Name |
Fosphenytoin |
| Drug ID |
BADD_D00970 |
| Description |
Fosphenytoin is a water-soluble phenytoin prodrug used only in hospitals for the treatment of epileptic seizures. It works by slowing down impulses in the brain that cause seizures. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials. |
| Indications and Usage |
For the control of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery. It can also be substituted, short-term, for oral phenytoin. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
N03AB05 |
| DrugBank ID |
DB01320
|
| KEGG ID |
D07993
|
| MeSH ID |
C043114
|
| PubChem ID |
56339
|
| TTD Drug ID |
D0J5YC
|
| NDC Product Code |
70121-1381; 70121-1390 |
| Synonyms |
fosphenytoin | 3-(hydroxymethyl)phenytoin phosphate ester | ACC 9653 | ACC-9653 | Prodilantin | fosphenytoin sodium | fosphenytoin, disodium salt | 3-(hydroxymethyl)phenytoin disodium phosphate | HMPDP | Cerebyx |
