Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Fosinoprilat
Drug ID BADD_D00969
Description Fosinoprilat is the active phosphinic acid metabolite of prodrug [fosinopril], which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
Indications and Usage Not Available
Marketing Status experimental
ATC Code Not Available
DrugBank ID DB14207
KEGG ID D03772
MeSH ID C046965
PubChem ID 62956
TTD Drug ID Not Available
NDC Product Code Not Available
UNII S312EY6ZT8
Synonyms fosinoprilat | fosinoprilic acid | fosfenopril | SQ 27519 | SQ-27519 | SQ-27,519
Chemical Information
Molecular Formula C23H34NO5P
CAS Registry Number 95399-71-6
SMILES C1CCC(CC1)C2CC(N(C2)C(=O)CP(=O)(CCCCC3=CC=CC=C3)O)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pharyngitis07.05.07.004; 22.07.03.004; 11.01.13.003--
Photosensitivity reaction23.03.09.0030.007032%
Pleuritic pain22.12.01.007--
Pollakiuria20.02.02.007--
Pruritus23.03.12.001--
Pseudolymphoma01.09.01.0160.010549%Not Available
Pulmonary eosinophilia22.01.01.009; 01.02.04.006--Not Available
Rash23.03.13.001--Not Available
Renal failure20.01.03.005--Not Available
Renal pain20.02.03.003--Not Available
Respiration abnormal22.02.01.041--Not Available
Respiratory disorder22.02.07.002--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Sensory loss17.02.07.007--Not Available
Sexual dysfunction21.03.02.003; 19.08.05.002--Not Available
Shock24.06.02.002--Not Available
Sinusitis22.07.03.007; 11.01.13.005--
Sleep disorder19.02.04.001--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Sudden death08.04.01.003; 02.03.04.013--
Swelling08.01.03.015--Not Available
Swollen tongue23.04.01.014; 10.01.05.015; 07.14.02.0030.014065%Not Available
Syncope02.11.04.015; 24.06.02.012; 17.02.04.008--
Tachycardia02.03.02.007--Not Available
Thrombocytopenia01.08.01.002--Not Available
Tinnitus04.04.01.002; 17.04.07.004--
Tracheobronchitis22.07.01.016; 11.01.09.020--Not Available
Tremor17.01.06.002--
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urticaria10.01.06.001; 23.04.02.001--
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